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Gene

SMN2

survival of motor neuron 2, centromeric

Summary

Cytogenetic location
5q13.2
Coordinates
Chromosome 5: 70,049,669–70,077,595 (GRCh38)
Exons
9 exons across 27.9 kb
Protein
294 amino acids
Also known as
BCD541, SMNC, GEMIN1, TDRD16B
MANE Select transcript
ENST00000380743.9NM_017411.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMN2 yet. The test sequences your whole genome, so your data includes it all the same.

How SMN2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 5, with a bracket where SMN2 sits. SMN2 and 6 genes near it on chromosome 5, from 69,563,632 to 70,563,631.Chromosome 55q13.2p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.369.6 Mb69.8 Mb70 Mb70.2 Mb70.4 MbGTF2H2C: 69,558,392–69,595,221, forward strandGTF2H2C: 69,632,080–69,636,399, forward strand: 69,898,769–69,903,085, reverse strandSERF1B: 70,025,241–70,043,113, forward strandSERF1BSMN2: 70,049,669–70,077,595, forward strandSMN2: 70,487,719–70,491,228, forward strand: 70,508,196–70,512,509, forward strandDiagram of SMN2: 9 exons on the forward strand of chromosome 5Exon 1: 70,049,669–70,049,766, 98 basesExon 2: 70,063,415–70,063,486, 72 basesExon 3: 70,065,965–70,066,084, 120 basesExon 4: 70,066,934–70,067,134, 201 basesExon 5: 70,067,294–70,067,446, 153 basesExon 6: 70,069,235–70,069,330, 96 basesExon 7: 70,070,641–70,070,751, 111 basesExon 8: 70,076,521–70,076,574, 54 basesExon 9: 70,077,019–70,077,595, 577 bases1246895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.5 kb of the gene's 27.9 kb; 885 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). SMN2 gene: survival of motor neuron 2, centromeric. Retrieved 17 October 2026, from https://dantelabs.com/genes/smn2

Vancouver

Dante Labs. SMN2 gene: survival of motor neuron 2, centromeric [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smn2

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