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Gene

GABBR1

gamma-aminobutyric acid type B receptor subunit 1

Summary

Cytogenetic location
6p22.1
Coordinates
Chromosome 6: 29,602,238–29,633,183 (GRCh38)
Exons
23 exons across 30.9 kb
Protein
961 amino acids
Also known as
hGB1a, GPRC3A
MANE Select transcript
ENST00000377034.9NM_001470.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads GABBR1 yet. The test sequences your whole genome, so your data includes it all the same.

How GABBR1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 6, with a bracket where GABBR1 sits. GABBR1 and 22 genes near it on chromosome 6, from 29,117,711 to 30,117,710.Chromosome 66p22.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2729.2 Mb29.4 Mb29.6 Mb29.8 Mb30 MbOR2J2: 29,170,907–29,175,811, forward strandOR2J2OR14J1: 29,301,701–29,313,017, forward strandOR14J1OR5V1: 29,353,749–29,431,967, reverse strandOR12D3: 29,373,423–29,375,291, reverse strandOR12D3OR12D2: 29,395,631–29,398,008, forward strandOR12D2OR12D1: 29,414,928–29,418,905, forward strandOR12D1OR11A1: 29,425,504–29,457,071, reverse strandOR11A1OR10C1: 29,439,306–29,440,977, forward strandOR10C1OR2H1: 29,457,155–29,464,328, forward strandOR2H1MAS1L: 29,486,697–29,487,956, reverse strandMAS1LOR2I1: 29,550,407–29,557,773, forward strandOR2I1UBD: 29,552,554–29,559,738, reverse strandUBDOR2H2: 29,585,121–29,590,500, forward strandOR2H2GABBR1: 29,602,238–29,633,183, reverse strandGABBR1MOG: 29,656,598–29,674,431, forward strandMOGZFP57: 29,672,482–29,681,174, reverse strandZFP57HLA-F: 29,722,738–29,740,358, forward strandHLA-FHLA-G: 29,826,967–29,831,130, forward strandHLA-GHLA-A: 29,941,260–29,949,606, forward strandHLA-APOLR1H: 30,058,899–30,064,909, forward strandPOLR1HPPP1R11: 30,066,709–30,074,025, forward strandPPP1R11RNF39: 30,070,266–30,075,849, reverse strandRNF39TRIM31: 30,102,886–30,113,126, reverse strandTRIM31Diagram of GABBR1: 23 exons on the reverse strand of chromosome 6Exon 21: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 11: 1 known disease-causing siteExon 23: 29,602,238–29,603,716, 1,479 basesExon 22: 29,604,494–29,604,637, 144 basesExon 21: 29,604,860–29,604,988, 129 basesExon 20: 29,605,569–29,605,696, 128 basesExon 19: 29,606,391–29,606,484, 94 basesExon 18: 29,606,897–29,607,004, 108 basesExon 17: 29,607,102–29,607,218, 117 basesExon 16: 29,608,601–29,608,733, 133 basesExon 15: 29,609,229–29,609,379, 151 basesExon 14: 29,610,924–29,611,001, 78 basesExon 13: 29,612,551–29,612,614, 64 basesExon 12: 29,613,243–29,613,485, 243 basesExon 11: 29,621,101–29,621,292, 192 basesExon 10: 29,621,752–29,621,817, 66 basesExon 9: 29,622,104–29,622,205, 102 basesExon 8: 29,623,305–29,623,475, 171 basesExon 7: 29,623,890–29,624,024, 135 basesExon 6: 29,627,486–29,627,646, 161 basesExon 5: 29,629,087–29,629,107, 21 basesExon 4: 29,630,458–29,630,643, 186 basesExon 3: 29,631,396–29,631,599, 204 basesExon 2: 29,632,301–29,632,385, 85 basesExon 1: 29,632,850–29,633,183, 334 bases2322201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.5 kb of the gene's 30.9 kb; 2,886 of those bases code for the protein.

How a genome test reads GABBR1

3

positions in GABBR1 where ClinVar classes a change as pathogenic or likely pathogenic

3 of them (100%) fall in regions short reads find hard.

  • MHC (3 sites)The major histocompatibility complex (HLA genes), highly polymorphic and poorly represented by a single reference.

A whole genome covers all 30.9 kb of GABBR1, introns included, not only the 4.5 kb of exons.

Traits linked to GABBR1

The Human Phenotype Ontology lists these as features of the rare conditions GABBR1 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GABBR1 gene: gamma-aminobutyric acid type B receptor subunit 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/gabbr1

Vancouver

Dante Labs. GABBR1 gene: gamma-aminobutyric acid type B receptor subunit 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gabbr1

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