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Gene

HLA-G

major histocompatibility complex, class I, G

Summary

Cytogenetic location
6p22.1
Coordinates
Chromosome 6: 29,827,825–29,831,021 (GRCh38)
Exons
7 exons across 3.2 kb
Protein
338 amino acids
MANE Select transcript
ENST00000360323.11NM_001384290.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HLA-G yet. The test sequences your whole genome, so your data includes it all the same.

How HLA-G is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 6, with a bracket where HLA-G sits. HLA-G and 26 genes near it on chromosome 6, from 29,329,423 to 30,329,422.Chromosome 66p22.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2729.4 Mb29.6 Mb29.8 Mb30 Mb30.2 MbOR5V1: 29,353,749–29,431,967, reverse strandOR12D3: 29,373,423–29,375,291, reverse strandOR12D3OR12D2: 29,395,631–29,398,008, forward strandOR12D2OR12D1: 29,414,928–29,418,905, forward strandOR12D1OR11A1: 29,425,504–29,457,071, reverse strandOR11A1OR10C1: 29,439,306–29,440,977, forward strandOR10C1OR2H1: 29,457,155–29,464,328, forward strandOR2H1MAS1L: 29,486,697–29,487,956, reverse strandMAS1LOR2I1: 29,550,407–29,557,773, forward strandOR2I1GABBR1: 29,552,554–29,633,976, reverse strandGABBR1UBD: 29,552,554–29,559,738, reverse strandUBDOR2H2: 29,585,121–29,590,500, forward strandOR2H2MOG: 29,656,598–29,674,431, forward strandMOGZFP57: 29,672,482–29,681,174, reverse strandZFP57HLA-F: 29,722,738–29,740,358, forward strandHLA-FHLA-G: 29,827,825–29,831,021, forward strandHLA-GHLA-A: 29,941,260–29,949,606, forward strandHLA-APOLR1H: 30,058,899–30,064,909, forward strandPOLR1HPPP1R11: 30,066,709–30,074,025, forward strandPPP1R11RNF39: 30,070,266–30,075,849, reverse strandRNF39TRIM31: 30,102,886–30,113,126, reverse strandTRIM31TRIM40: 30,136,028–30,151,592, forward strandTRIM40TRIM10: 30,151,943–30,161,288, reverse strandTRIM10TRIM15: 30,163,194–30,173,160, forward strandTRIM15TRIM26: 30,184,446–30,214,158, reverse strandTRIM26TRIM39: 30,325,880–30,344,265, forward strandTRIM39TRIM39-RPP21: 30,328,907–30,346,854, forward strandTRIM39-RPP21Diagram of HLA-G: 7 exons on the forward strand of chromosome 6Exon 1: 29,827,825–29,827,917, 93 basesExon 2: 29,828,047–29,828,316, 270 basesExon 3: 29,828,543–29,828,818, 276 basesExon 4: 29,829,418–29,829,693, 276 basesExon 5: 29,829,816–29,829,932, 117 basesExon 6: 29,830,378–29,830,410, 33 basesExon 7: 29,830,768–29,831,021, 254 bases12345675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.3 kb of the gene's 3.2 kb; 1,017 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). HLA-G gene: major histocompatibility complex, class I, G. Retrieved 16 October 2026, from https://dantelabs.com/genes/hla-g

Vancouver

Dante Labs. HLA-G gene: major histocompatibility complex, class I, G [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/hla-g

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