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Gene

DUX4

double homeobox 4

Summary

Cytogenetic location
4q35.2
Coordinates
Chromosome 4: 190,173,774–190,175,845 (GRCh38)
Exons
2 exons across 2.1 kb
Protein
424 amino acids
MANE Select transcript
ENST00000565211.1NM_001306068.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DUX4 yet. The test sequences your whole genome, so your data includes it all the same.

How DUX4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 4, with a bracket where DUX4 sits. DUX4 and 3 genes near it on chromosome 4, from 189,674,810 to 190,674,809.Chromosome 44q35.2p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.2189.8 Mb190 Mb190.2 Mb190.4 Mb190.6 MbFRG1: 189,940,818–189,963,207, forward strandFRG1DUX4L9: 190,019,718–190,022,665, reverse strandDUX4L9FRG2: 190,024,367–190,027,257, reverse strandFRG2DUX4: 190,173,774–190,175,845, forward strandDUX4Diagram of DUX4: 2 exons on the forward strand of chromosome 4Exon 1: 190,173,774–190,175,284, 1,511 basesExon 2: 190,175,647–190,175,845, 199 bases125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.7 kb of the gene's 2.1 kb; 1,275 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). DUX4 gene: double homeobox 4. Retrieved 16 October 2026, from https://dantelabs.com/genes/dux4

Vancouver

Dante Labs. DUX4 gene: double homeobox 4 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dux4

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