Trait

Supraventricular arrhythmia

A type of arrhythmia that originates above the ventricles, whereby the electrical impulse propagates down the normal His Purkinje system similar to normal sinus rhythm.

HPO HP:0005115

Also called: Supraventricular arrhythmias
Body system: Abnormality of the cardiovascular system

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29 genes linked to Supraventricular arrhythmia

Changes in these genes cause rare conditions in which Supraventricular arrhythmia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
LMNAlamin A/C	Very often (80–99%)	In 4 conditions
COL4A1collagen type IV alpha 1 chain	Often (30–79%)	In 1 condition
DESdesmin	Often (30–79%)	In 1 condition
ACTC1actin alpha cardiac muscle 1	Sometimes (5–29%)	In 1 condition
CDH23cadherin related 23	Sometimes (5–29%)	In 1 condition
CITED2Cbp/p300 interacting transactivator with ED-rich tail 2	Sometimes (5–29%)	In 2 conditions
CIZ1CDKN1A interacting zinc finger protein 1	Sometimes (5–29%)	In 1 condition
DNMT3BDNA methyltransferase 3 beta	Sometimes (5–29%)	In 1 condition
DUX4double homeobox 4	Sometimes (5–29%)	In 1 condition
DUX4L1double homeobox 4 like 1 (pseudogene)	Sometimes (5–29%)	In 1 condition
EMDemerin	Sometimes (5–29%)	In 1 condition
FHL1four and a half LIM domains 1	Sometimes (5–29%)	In 1 condition
FLNCfilamin C	Sometimes (5–29%)	In 1 condition
FRG1FSHD region gene 1	Sometimes (5–29%)	In 1 condition
GATA4GATA binding protein 4	Sometimes (5–29%)	In 1 condition
GATA6GATA binding protein 6	Sometimes (5–29%)	In 1 condition
KIF20Akinesin family member 20A	Sometimes (5–29%)	In 1 condition
MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6	Sometimes (5–29%)	In 1 condition
MYH6myosin heavy chain 6	Sometimes (5–29%)	In 1 condition
MYPNmyopalladin	Sometimes (5–29%)	In 1 condition
NKX2-5NK2 homeobox 5	Sometimes (5–29%)	In 1 condition
SMCHD1structural maintenance of chromosomes flexible hinge domain containing 1	Sometimes (5–29%)	In 1 condition
SYNE1spectrin repeat containing nuclear envelope protein 1	Sometimes (5–29%)	In 1 condition
SYNE2spectrin repeat containing nuclear envelope protein 2	Sometimes (5–29%)	In 1 condition
TBX20T-box transcription factor 20	Sometimes (5–29%)	In 1 condition
TLL1tolloid like 1	Sometimes (5–29%)	In 1 condition
TMEM43transmembrane protein 43	Sometimes (5–29%)	In 1 condition
TNNI3troponin I3, cardiac type	Sometimes (5–29%)	In 1 condition
TNNT2troponin T2, cardiac type	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Broader traits

Abnormal heart rate

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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