Gene
ADAT3
adenosine deaminase tRNA specific 3
- HGNC 25151↗(opens in a new tab)
- Ensembl gene ENSG00000213638↗(opens in a new tab)
- NCBI Gene 113179↗(opens in a new tab)
Summary
- Cytogenetic location
- 19p13.3
- Coordinates
- Chromosome 19: 1,905,399–1,913,447 (GRCh38)
- Exons
- 2 exons across 8 kb
- Protein
- 367 amino acids
- Also known as
- TAD3
- MANE Select transcript
- ENST00000329478.4NM_138422.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads ADAT3 yet. The test sequences your whole genome, so your data includes it all the same.
How ADAT3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.6 kb of the gene's 8 kb; 1,104 of those bases code for the protein.
How a genome test reads ADAT3
5
positions in ADAT3 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 8 kb of ADAT3, introns included, not only the 1.6 kb of exons.
Traits linked to ADAT3
The Human Phenotype Ontology lists these as features of the rare conditions ADAT3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Intellectual disability
- Abnormal shape of brain
- Delayed speech and language development
- Global developmental delay
- Aggressive behavior
- Brain degeneration
- Delayed CNS myelination
- Delayed myelination
Show 11 more traits
- Diffuse demyelination of the cerebral white matter
- Epilepsy
- Fluid-filled sac located in membrane surrounding brain or spinal cord
- Impulsivity
- More active than typical
- Ventriculomegaly
- Abnormal gait
- Agenesis of corpus callosum
- Balance impairment
- Peripheral neuropathy
- Underdevelopment of part of brain called corpus callosum
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). ADAT3 gene: adenosine deaminase tRNA specific 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/adat3
Dante Labs. ADAT3 gene: adenosine deaminase tRNA specific 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/adat3
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