Trait

Volvulus

Abnormal twisting of a portion of intestine around itself or around a stalk of mesentery tissue.

Body system: Abnormality of the digestive system

This page as data

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page <- fromJSON(url)
page$trait$name

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21 genes linked to Volvulus

Changes in these genes cause rare conditions in which Volvulus is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
RNU2-2RNA, U2 small nuclear 2	Always	In 1 condition
VPS51VPS51 subunit of GARP complex	Always	In 1 condition
ZMYM3zinc finger MYM-type containing 3	Always	In 1 condition
TEKTEK receptor tyrosine kinase	Often (30–79%)	In 1 condition
VARS1valyl-tRNA synthetase 1	Often (30–79%)	In 1 condition
AP1S1adaptor related protein complex 1 subunit sigma 1	Sometimes (5–29%)	In 1 condition
ATRXATRX chromatin remodeler	Sometimes (5–29%)	In 1 condition
BRD4bromodomain containing 4	Sometimes (5–29%)	In 1 condition
CHRM3cholinergic receptor muscarinic 3	Sometimes (5–29%)	In 1 condition
EFEMP1EGF-like fibulin extracellular matrix protein 1	Sometimes (5–29%)	In 1 condition
EXT2exostosin glycosyltransferase 2	Sometimes (5–29%)	In 1 condition
FOXF1forkhead box F1	Sometimes (5–29%)	In 1 condition
HDAC8histone deacetylase 8	Sometimes (5–29%)	In 1 condition
MAU2MAU2 sister chromatid cohesion factor	Sometimes (5–29%)	In 1 condition
MYH11myosin heavy chain 11	Sometimes (5–29%)	In 1 condition
NIPBLNIPBL cohesin loading factor	Sometimes (5–29%)	In 1 condition
RAD21RAD21 cohesin complex component	Sometimes (5–29%)	In 1 condition
SMC1Astructural maintenance of chromosomes 1A	Sometimes (5–29%)	In 1 condition
SMC3structural maintenance of chromosomes 3	Sometimes (5–29%)	In 1 condition
DIS3L2DIS3 like 3'-5' exoribonuclease 2	Not recorded	In 1 condition
PACS1phosphofurin acidic cluster sorting protein 1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormality of the intestine

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

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