Trait
Knee contracture
Lack of full passive range of motion (restrictions in flexion, extension, or other movements) of the knee joint resulting from structural changes of non-bony tissues, such as muscles, tendons, ligaments, joint capsules and/or skin.
Summary
- Also called
- Contracture of knee, Contracture of the knees, Knee contractures
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Knee contracture, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test20 genes linked to Knee contracture
Changes in these genes cause rare conditions in which Knee contracture is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GNPATglyceronephosphate O-acyltransferase | Always | In 1 condition |
| GTPBP2GTP binding protein 2 | Always | In 1 condition |
| NDC1NDC1 transmembrane nucleoporin | Always | In 1 condition |
| UNC13Aunc-13 homolog A | Always | In 1 condition |
| COL6A2collagen type VI alpha 2 chain | Very often (80–99%) | In 2 conditions |
| COL6A3collagen type VI alpha 3 chain | Very often (80–99%) | In 1 condition |
| ACTA1actin alpha 1, skeletal muscle | Often (30–79%) | In 1 condition |
| BORCS8BLOC-1 related complex subunit 8 | Often (30–79%) | In 1 condition |
| CFL2cofilin 2 | Often (30–79%) | In 1 condition |
| COX11cytochrome c oxidase copper chaperone COX11 | Often (30–79%) | In 1 condition |
| DHRSXdehydrogenase/reductase X-linked | Often (30–79%) | In 1 condition |
| EPG5ectopic P-granules 5 autophagy tethering factor | Often (30–79%) | In 1 condition |
| FBN2fibrillin 2 | Often (30–79%) | In 1 condition |
| FILIP1filamin A interacting protein 1 | Often (30–79%) | In 1 condition |
| MEGF10multiple EGF like domains 10 | Often (30–79%) | In 1 condition |
| UGGT1UDP-glucose glycoprotein glucosyltransferase 1 | Often (30–79%) | In 1 condition |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Sometimes (5–29%) | In 1 condition |
| LMNAlamin A/C | Sometimes (5–29%) | In 1 condition |
| SCARF2scavenger receptor class F member 2 | Sometimes (5–29%) | In 1 condition |
| SCN4Asodium voltage-gated channel alpha subunit 4 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks