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Trait

Frontal balding

Absence of hair in the anterior midline and/or parietal areas.

HPO HP:0002292

Summary

Also called
Male pattern baldness
Body system
Abnormality of the integument

17 genes linked to Frontal balding

Changes in these genes cause rare conditions in which Frontal balding is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
WNT4Wnt family member 4Very often (80–99%)In 1 condition
PQBP1polyglutamine binding protein 1Often (30–79%)In 1 condition
ABCD1ATP binding cassette subfamily D member 1Sometimes (5–29%)In 1 condition
ALMS1ALMS1 centrosome and basal body associated proteinSometimes (5–29%)In 1 condition
NR3C1nuclear receptor subfamily 3 group C member 1Sometimes (5–29%)In 1 condition
AP2M1adaptor related protein complex 2 subunit mu 1Rarely (1–4%)In 1 condition
CHD2chromodomain helicase DNA binding protein 2Rarely (1–4%)In 1 condition
GJA5gap junction protein alpha 5Rarely (1–4%)In 1 condition
GJA8gap junction protein alpha 8Rarely (1–4%)In 1 condition
NEXMIFneurite extension and migration factorRarely (1–4%)In 1 condition
RNU4-2RNA, U4 small nuclear 2Rarely (1–4%)In 1 condition
SCN1Asodium voltage-gated channel alpha subunit 1Rarely (1–4%)In 1 condition
SLC2A1solute carrier family 2 member 1Rarely (1–4%)In 1 condition
SLC6A1solute carrier family 6 member 1Rarely (1–4%)In 1 condition
SYNGAP1synaptic Ras GTPase activating protein 1Rarely (1–4%)In 1 condition
CNBPCCHC-type zinc finger nucleic acid binding proteinNot recordedIn 1 condition
DMPKDM1 protein kinaseNot recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Acquired abnormal hair pattern

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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