Traits

Traits linked to KIF14

kinesin family member 14

The Human Phenotype Ontology links 51 traits to KIF14, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	How often it is seen
Small cerebellum	Always
Small cerebrum	Always
Global developmental delay	Very often (80–99%)
Gray matter heterotopia	Very often (80–99%)
Intellectual disability, severe	Very often (80–99%)
Agenesis of cerebellar vermis	Often (30–79%)
Agenesis of corpus callosum	Often (30–79%)
Arrhinencephaly	Often (30–79%)
Delayed motor skills	Often (30–79%)
Fewer and broader ridges in brain	Often (30–79%)
Increased reflexes	Often (30–79%)
Underdeveloped frontal lobe	Often (30–79%)
Ventriculomegaly	Often (30–79%)
Attention deficit	Sometimes (5–29%)
Microlissencephaly	Sometimes (5–29%)
Underdevelopment of part of brain called corpus callosum	Sometimes (5–29%)
Intellectual disability	Not recorded
Poor speech	Not recorded
Simplified gyral pattern	Not recorded
Small cerebral cortex	Not recorded

Abnormality of the genitourinary system

Trait	How often it is seen
Small uterus	Always
Abnormally closed or absent vagina	Often (30–79%)
Absent kidney on one side	Often (30–79%)
Bilateral renal agenesis	Often (30–79%)
Small kidneys	Often (30–79%)
Ureteral hypoplasia	Often (30–79%)
Vesicoureteral reflux	Often (30–79%)
Ureteral agenesis	Sometimes (5–29%)
Hyperechogenic kidneys	Rarely (1–4%)

Abnormality of head or neck

Trait	How often it is seen
Abnormally small head	Always
Sloping forehead	Very often (80–99%)
Thin red part of the upper lip	Very often (80–99%)
Upward slanting of the opening between the eyelids	Very often (80–99%)
Bifid uvula	Often (30–79%)
Little lower jaw	Often (30–79%)
Nasal tip, upturned	Often (30–79%)
Wide nasal bridge	Often (30–79%)

Abnormality of the eye

Trait	How often it is seen
Abnormally small eyeball	Often (30–79%)
Cross-eyed	Often (30–79%)
Optic nerve hypoplasia	Often (30–79%)
Blindness	Not recorded

Abnormality of the musculoskeletal system

Trait	How often it is seen
Arthrogryposis multiplex congenita	Always
Abnormal cortical bone morphology	Often (30–79%)
Generalized decreased muscle tone	Not recorded

Growth abnormality

Trait	How often it is seen
Prenatal growth deficiency	Always
Growth delay	Very often (80–99%)
Short stature	Very often (80–99%)

Abnormality of limbs

Trait	How often it is seen
Rocker bottom foot	Often (30–79%)

Abnormality of prenatal development or birth

Trait	How often it is seen
Low levels of amniotic fluid	Often (30–79%)

Abnormality of the ear

Trait	How often it is seen
Low-set ears	Often (30–79%)

Abnormality of the integument

Trait	How often it is seen
Antecubital pterygium	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to KIF14 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test