Traits

Traits linked to IFT81

intraflagellar transport 81

The Human Phenotype Ontology links 27 traits to IFT81, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of head or neck

Trait	How often it is seen
Long, narrow head	Always
Prominent back of the head	Always
Relatively large head	Always
Long philtrum	Often (30–79%)
Midface retrusion	Often (30–79%)
Depressed nasal bridge	Not recorded
Prominent forehead	Not recorded

Abnormality of the musculoskeletal system

Trait	How often it is seen
Generalized decreased muscle tone	Always
Short ribs	Often (30–79%)
Hook-shaped collarbone	Not recorded
Horizontal ribs	Not recorded
Narrow chest	Not recorded
Small chest	Not recorded
Small wings of the pelvic girdle	Not recorded

Abnormality of limbs

Trait	How often it is seen
Postaxial polydactyly	Often (30–79%)
Smaller or shorter than typical limbs	Often (30–79%)
Short fingers or toes	Not recorded
Underdeveloped outer large forearm bone	Not recorded
Webbed fingers or toes	Not recorded

Abnormality of the respiratory system

Trait	How often it is seen
Breathing difficulties	Not recorded
Poorly developed lungs	Not recorded
Respiratory failure	Not recorded

Abnormality of the cardiovascular system

Trait	How often it is seen
Hole in heart wall separating two lower heart chambers	Often (30–79%)

Abnormality of the digestive system

Trait	How often it is seen
Omphalocele	Not recorded

Abnormality of the ear

Trait	How often it is seen
Low-set ears	Often (30–79%)

Abnormality of the eye

Trait	How often it is seen
Bulging eye	Not recorded

Abnormality of the genitourinary system

Trait	How often it is seen
Ambiguous external genitalia	Not recorded

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to IFT81 and how often each is seen. Find out more at hpo.jax.org.

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