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Gene

KHK

ketohexokinase

Summary

Cytogenetic location
2p23.3
Coordinates
Chromosome 2: 27,086,772–27,100,762 (GRCh38)
Exons
8 exons across 14 kb
Protein
298 amino acids
MANE Select transcript
ENST00000260598.10NM_006488.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KHK yet. The test sequences your whole genome, so your data includes it all the same.

How KHK is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where KHK sits. KHK and 35 genes near it on chromosome 2, from 26,593,767 to 27,593,766.Chromosome 22p23.3p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.326.6 Mb26.8 Mb27 Mb27.2 Mb27.4 MbCIB4: 26,579,428–26,641,366, reverse strandCIB4KCNK3: 26,692,713–26,733,420, forward strandKCNK3SLC35F6: 26,764,240–26,781,231, forward strandSLC35F6CENPA: 26,764,289–26,801,067, forward strandCENPADPYSL5: 26,847,747–26,950,351, forward strandDPYSL5MAPRE3: 26,970,400–27,027,219, forward strandMAPRE3TMEM214: 27,032,910–27,041,697, forward strandTMEM214AGBL5: 27,042,364–27,070,622, forward strandOST4: 27,058,735–27,073,830, reverse strandOST4EMILIN1: 27,078,044–27,086,408, forward strandEMILIN1KHK: 27,086,772–27,100,762, forward strandKHKCGREF1: 27,098,853–27,119,139, reverse strandCGREF1ABHD1: 27,123,789–27,130,812, forward strandABHD1PREB: 27,129,153–27,134,689, reverse strandPRR30: 27,136,848–27,139,410, reverse strandTCF23: 27,148,999–27,156,974, forward strandTCF23SLC5A6: 27,199,587–27,212,958, reverse strandSLC5A6ATRAID: 27,212,012–27,217,178, forward strandATRAIDCAD: 27,217,345–27,245,683, forward strandCADSLC30A3: 27,253,509–27,275,817, reverse strandSLC30A3DNAJC5G: 27,275,430–27,281,499, forward strandDNAJC5GTRIM54: 27,282,366–27,309,400, forward strandTRIM54UCN: 27,307,400–27,308,445, reverse strandUCNMPV17: 27,309,486–27,325,680, reverse strandGTF3C2: 27,324,198–27,357,566, reverse strandGTF3C2EIF2B4: 27,363,420–27,370,466, reverse strandEIF2B4SNX17: 27,370,496–27,377,535, forward strandSNX17ZNF513: 27,377,235–27,380,790, reverse strandZNF513PPM1G: 27,381,194–27,409,674, reverse strandNRBP1: 27,427,790–27,442,260, forward strandNRBP1KRTCAP3: 27,442,337–27,446,486, forward strandKRTCAP3IFT172: 27,444,374–27,489,839, reverse strandIFT172FNDC4: 27,491,260–27,495,631, reverse strandFNDC4GCKR: 27,496,055–27,523,688, forward strandGCKRSPATA31H1: 27,537,386–27,582,722, forward strandSPATA31H1ZNF512: 27,582,969–27,623,217, forward strandZNF512Diagram of KHK: 8 exons on the forward strand of chromosome 2Exon 1: 27,086,772–27,087,351, 580 basesExon 2: 27,092,332–27,092,448, 117 basesExon 3: 27,094,800–27,094,934, 135 basesExon 4: 27,096,729–27,096,801, 73 basesExon 5: 27,097,503–27,097,649, 147 basesExon 6: 27,099,196–27,099,284, 89 basesExon 7: 27,099,420–27,099,577, 158 basesExon 8: 27,099,665–27,100,762, 1,098 bases123456785′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 14 kb; 897 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). KHK gene: ketohexokinase. Retrieved 17 October 2026, from https://dantelabs.com/genes/khk

Vancouver

Dante Labs. KHK gene: ketohexokinase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/khk

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