Trait
Unequal size of red blood cells
Clinical name: Anisocytosis
Abnormally increased variability in the size of erythrocytes.
Summary
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page$trait$nameRead the genes linked to Unequal size of red blood cells, and the rest of your genome, with one test.
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Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Congenital Dyserythropoietic AnaemiasReads 3 of these genesKLF1CDAN1CDIN1About this report →
- Hereditary Sideroblastic AnaemiasReads 3 of these genesABCB7TRNT1GLRX5About this report →
- G6PD DeficiencyReads 1 of these genesG6PDAbout this report →
- Sickle Cell DiseaseReads 1 of these genesHBBAbout this report →
Show 13 more reports
- Red Blood Cell Membrane DisordersReads 2 of these genesRHAGRHCEAbout this report →
- Rare Inherited Megaloblastic AnaemiasReads 1 of these genesUMPSAbout this report →
- Inherited Iron Metabolism DisordersReads 1 of these genesTMPRSS6About this report →
- Hereditary Methaemoglobinaemia and Unstable HaemoglobinsReads 1 of these genesHBBAbout this report →
- ThalassaemiaReads 1 of these genesHBBAbout this report →
- PolycythemiaReads 1 of these genesHBBAbout this report →
- Pyruvate Kinase Deficiency and Other Red Cell Enzyme DisordersReads 1 of these genesPKLRAbout this report →
- PorphyriaReads 1 of these genesUROSAbout this report →
- Diamond-Blackfan AnemiaReads 1 of these genesGATA1About this report →
- Inherited ThrombocytopeniasReads 1 of these genesGATA1About this report →
- Rare Monogenic Autoinflammatory DiseasesReads 1 of these genesDOCK11About this report →
- Intellectual DisabilityReads 1 of these genesCASKAbout this report →
- Inherited Neurodegenerative DisordersReads 1 of these genesABCB7About this report →
Read the genes linked to Unequal size of red blood cells, and the rest of your genome, with one test.
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Get my Genome Test23 genes linked to Unequal size of red blood cells
Changes in these genes cause rare conditions in which Unequal size of red blood cells is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCB7ATP binding cassette subfamily B member 7 | Always | In 2 conditions |
| ATPAF2ATP synthase mitochondrial F1 complex assembly factor 2 | Always | In 1 condition |
| DOCK11dedicator of cytokinesis 11 | Always | In 1 condition |
| FLT3LGfms related receptor tyrosine kinase 3 ligand | Always | In 1 condition |
| GATA1GATA binding protein 1 | Always | In 3 conditions |
| KLF1KLF transcription factor 1 | Always | In 2 conditions |
| KIF23kinesin family member 23 | Very often (80–99%) | In 1 condition |
| RACGAP1Rac GTPase activating protein 1 | Very often (80–99%) | In 1 condition |
| HBBhemoglobin subunit beta | Often (30–79%) | In 1 condition |
| TRNT1tRNA nucleotidyl transferase 1 | Often (30–79%) | In 1 condition |
| PKLRpyruvate kinase L/R | Sometimes (5–29%) | In 1 condition |
| RHAGRh associated glycoprotein | Sometimes (5–29%) | In 2 conditions |
| RHCERh blood group CcEe antigens | Sometimes (5–29%) | In 2 conditions |
| RHDRh blood group D antigen | Sometimes (5–29%) | In 1 condition |
| RPS14ribosomal protein S14 | Sometimes (5–29%) | In 1 condition |
| UROSuroporphyrinogen III synthase | Sometimes (5–29%) | In 1 condition |
| CASKcalcium/calmodulin dependent serine protein kinase | Not recorded | In 1 condition |
| CDAN1codanin 1 | Not recorded | In 1 condition |
| CDIN1CDAN1 interacting nuclease 1 | Not recorded | In 1 condition |
| G6PDglucose-6-phosphate dehydrogenase | Not recorded | In 1 condition |
| GLRX5glutaredoxin 5 | Not recorded | In 1 condition |
| TMPRSS6transmembrane serine protease 6 | Not recorded | In 1 condition |
| UMPSuridine monophosphate synthetase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.19-9814e911.
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