Trait
Shyness
Clinical name: Excessive shyness
Atypically high degree of awkwardness or apprehension experienced when approaching or being approached by others.
Summary
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Shyness, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test12 genes linked to Shyness
Changes in these genes cause rare conditions in which Shyness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AP4S1adaptor related protein complex 4 subunit sigma 1 | Always | In 2 conditions |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| DPYDdihydropyrimidine dehydrogenase | Very often (80–99%) | In 1 condition |
| AP4B1adaptor related protein complex 4 subunit beta 1 | Often (30–79%) | In 2 conditions |
| AP4E1adaptor related protein complex 4 subunit epsilon 1 | Often (30–79%) | In 2 conditions |
| NONOnon-POU domain containing octamer binding | Often (30–79%) | In 1 condition |
| AP4M1adaptor related protein complex 4 subunit mu 1 | Sometimes (5–29%) | In 1 condition |
| FERRY3FERRY endosomal RAB5 effector complex subunit 3 | Sometimes (5–29%) | In 1 condition |
| POLA1DNA polymerase alpha 1, catalytic subunit | Sometimes (5–29%) | In 1 condition |
| RPS6KC1ribosomal protein S6 kinase C1 | Sometimes (5–29%) | In 1 condition |
| RLIMring finger protein, LIM domain interacting | Not recorded | In 1 condition |
| SETD2SET domain containing 2, histone lysine methyltransferase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks