Trait
Aortic valve calcification
Deposition of calcium salts in the aortic valve.
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test11 genes linked to Aortic valve calcification
Changes in these genes cause rare conditions in which Aortic valve calcification is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GATA5GATA binding protein 5 | Very often (80–99%) | In 1 condition |
| LMNAlamin A/C | Very often (80–99%) | In 2 conditions |
| NKX2-5NK2 homeobox 5 | Very often (80–99%) | In 1 condition |
| NOTCH1notch receptor 1 | Very often (80–99%) | In 2 conditions |
| ROBO4roundabout guidance receptor 4 | Very often (80–99%) | In 1 condition |
| SMAD6SMAD family member 6 | Very often (80–99%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Often (30–79%) | In 3 conditions |
| HGDhomogentisate 1,2-dioxygenase | Often (30–79%) | In 2 conditions |
| RIGIRNA sensor RIG-I | Often (30–79%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Sometimes (5–29%) | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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