Gene
TRIM44
TRIM family member 44
- HGNC 19016↗(opens in a new tab)
- Ensembl gene ENSG00000166326↗(opens in a new tab)
- NCBI Gene 54765↗(opens in a new tab)
Summary
- Cytogenetic location
- 11p13
- Coordinates
- Chromosome 11: 35,662,775–35,818,007 (GRCh38)
- Exons
- 5 exons across 155.2 kb
- Protein
- 344 amino acids
- Also known as
- DIPB, MC7
- MANE Select transcript
- ENST00000299413.7NM_017583.6
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/genes/trim44.json"
page <- fromJSON(url)
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How TRIM44 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 13 kb of the gene's 155.2 kb; 1,035 of those bases code for the protein.
Sequencing TRIM44
1Easy
How hard TRIM44 is to sequence with short reads, out of 100
0 · Easy100 · Hard
Almost all of TRIM44's exons sit where short reads map cleanly.
What adds to it: the share of TRIM44's exons in each kind of hard region
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. Weight 35%.0%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. Weight 30%.0%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. Weight 15%.3.8%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. Weight 10%.4.8%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. Weight 10%.0%
A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scoredEach bar is the share of TRIM44's exon bases in that kind of difficult region. The score weighs them by how much each costs a short-read call: 0 when no base is in any, 100 when every base is in all of them.
Traits linked to TRIM44
The Human Phenotype Ontology lists these as features of the rare conditions TRIM44 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the eye
- Absent iris
- Decreased clarity of vision
- Aplasia/Hypoplasia of the macula
- Hypoplasia of the fovea
- Involuntary, rapid, rhythmic eye movements
- Underdeveloped iris
- Visual loss
- Abnormal foveal pit on macular OCT
Show 18 more traits
- Abnormal full-field electroretinogram
- Abnormal multifocal electroretinogram
- Clouding of the lens of the eye
- Corneal opacity
- Cross-eyed
- Ectopia lentis
- Fundus hypopigmentation
- Glaucoma
- Limbal stem cell deficiency
- New blood vessel formation in cornea
- Peters anomaly
- Red green color blindness
- Abnormally small eyeball
- Drooping upper eyelid
- Extreme sensitivity of the eyes to light
- Optic nerve hypoplasia
- Lens coloboma
- Microspherophakia
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). TRIM44 gene: TRIM family member 44. Retrieved 18 October 2026, from https://dantelabs.com/genes/trim44
Dante Labs. TRIM44 gene: TRIM family member 44 [Internet]. [cited 18 October 2026]. Available from: https://dantelabs.com/genes/trim44
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