{
  "url": "https://dantelabs.com/genes/trim44",
  "gene": {
    "slug": "trim44",
    "symbol": "TRIM44",
    "name": "TRIM family member 44",
    "hgnc": "HGNC:19016",
    "summary": null,
    "location": "11p13",
    "locusType": "gene with protein product",
    "aliases": [
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      "MC7"
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    "previousSymbols": [],
    "ensemblId": "ENSG00000166326",
    "entrezId": 54765,
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    "uniprot": [
      "Q96DX7"
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    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "11",
      "start": 35662775,
      "end": 35818007,
      "strand": "+",
      "ensemblTranscript": "ENST00000299413.7",
      "refseqTranscript": "NM_017583.6",
      "ensemblProtein": "ENSP00000299413.5",
      "refseqProtein": "NP_060053.2",
      "exons": [
        {
          "start": 35662775,
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        },
        {
          "start": 35685259,
          "end": 35685336
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        {
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          "start": 35735426,
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        },
        {
          "start": 35806358,
          "end": 35818007
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      ],
      "cds": {
        "start": 35663112,
        "end": 35806385
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    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "11",
      "start": 35684353,
      "end": 35829775,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 35240391,
      "end": 36240390,
      "genes": [
        {
          "symbol": "SLC1A2",
          "ensemblId": "ENSG00000110436",
          "biotype": "protein_coding",
          "start": 35251205,
          "end": 35420063,
          "strand": "-",
          "slug": "slc1a2"
        },
        {
          "symbol": "PAMR1",
          "ensemblId": "ENSG00000149090",
          "biotype": "protein_coding",
          "start": 35431823,
          "end": 35530300,
          "strand": "-",
          "slug": "pamr1"
        },
        {
          "symbol": "FJX1",
          "ensemblId": "ENSG00000179431",
          "biotype": "protein_coding",
          "start": 35618460,
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          "strand": "+",
          "slug": "fjx1"
        },
        {
          "symbol": "LDLRAD3",
          "ensemblId": "ENSG00000179241",
          "biotype": "protein_coding",
          "start": 35943981,
          "end": 36274286,
          "strand": "+",
          "slug": "ldlrad3"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-foveal-pit-on-macular-oct",
        "name": "Abnormal foveal pit on macular OCT",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-foveal-pit-on-macular-oct"
      },
      {
        "slug": "abnormal-full-field-electroretinogram",
        "name": "Abnormal full-field electroretinogram",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-full-field-electroretinogram"
      },
      {
        "slug": "abnormal-multifocal-electroretinogram",
        "name": "Abnormal multifocal electroretinogram",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-multifocal-electroretinogram"
      },
      {
        "slug": "microphthalmia",
        "name": "Abnormally small eyeball",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/microphthalmia"
      },
      {
        "slug": "aniridia",
        "name": "Absent iris",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/aniridia"
      },
      {
        "slug": "aplasia-hypoplasia-of-the-macula",
        "name": "Aplasia/Hypoplasia of the macula",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/aplasia-hypoplasia-of-the-macula"
      },
      {
        "slug": "cataract",
        "name": "Clouding of the lens of the eye",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/cataract"
      },
      {
        "slug": "corneal-opacity",
        "name": "Corneal opacity",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/corneal-opacity"
      },
      {
        "slug": "strabismus",
        "name": "Cross-eyed",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/strabismus"
      },
      {
        "slug": "reduced-visual-acuity",
        "name": "Decreased clarity of vision",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/reduced-visual-acuity"
      },
      {
        "slug": "ptosis",
        "name": "Drooping upper eyelid",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ptosis"
      },
      {
        "slug": "keratoconjunctivitis-sicca",
        "name": "Dry eye syndrome",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-eye",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/keratoconjunctivitis-sicca"
      },
      {
        "slug": "ectopia-lentis",
        "name": "Ectopia lentis",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/ectopia-lentis"
      },
      {
        "slug": "photophobia",
        "name": "Extreme sensitivity of the eyes to light",
        "systems": [
          "abnormality-of-the-eye",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/photophobia"
      },
      {
        "slug": "fundus-hypopigmentation",
        "name": "Fundus hypopigmentation",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fundus-hypopigmentation"
      },
      {
        "slug": "glaucoma",
        "name": "Glaucoma",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/glaucoma"
      },
      {
        "slug": "hypoplasia-of-the-fovea",
        "name": "Hypoplasia of the fovea",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hypoplasia-of-the-fovea"
      },
      {
        "slug": "nystagmus",
        "name": "Involuntary, rapid, rhythmic eye movements",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/nystagmus"
      },
      {
        "slug": "lens-coloboma",
        "name": "Lens coloboma",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/lens-coloboma"
      },
      {
        "slug": "limbal-stem-cell-deficiency",
        "name": "Limbal stem cell deficiency",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/limbal-stem-cell-deficiency"
      },
      {
        "slug": "microspherophakia",
        "name": "Microspherophakia",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/microspherophakia"
      },
      {
        "slug": "corneal-neovascularization",
        "name": "New blood vessel formation in cornea",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/corneal-neovascularization"
      },
      {
        "slug": "optic-nerve-hypoplasia",
        "name": "Optic nerve hypoplasia",
        "systems": [
          "abnormality-of-the-eye",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/optic-nerve-hypoplasia"
      },
      {
        "slug": "peters-anomaly",
        "name": "Peters anomaly",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/peters-anomaly"
      },
      {
        "slug": "red-green-dyschromatopsia",
        "name": "Red green color blindness",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/red-green-dyschromatopsia"
      },
      {
        "slug": "hypoplasia-of-the-iris",
        "name": "Underdeveloped iris",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/hypoplasia-of-the-iris"
      },
      {
        "slug": "visual-loss",
        "name": "Visual loss",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/visual-loss"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}