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Gene

TNPO2

transportin 2

Summary

Cytogenetic location
19p13.13
Coordinates
Chromosome 19: 12,699,201–12,723,932 (GRCh38)
Exons
26 exons across 24.7 kb
Protein
897 amino acids
Also known as
IPO3, KPNB2B, FLJ12155, TRN2
MANE Select transcript
ENST00000425528.6NM_001382241.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TNPO2 yet. The test sequences your whole genome, so your data includes it all the same.

How TNPO2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 19, with a bracket where TNPO2 sits. TNPO2 and 48 genes near it on chromosome 19, from 12,211,567 to 13,211,566.Chromosome 1919p13.13p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4312.4 Mb12.6 Mb12.8 Mb13 Mb13.2 MbZNF44: 12,224,686–12,294,883, reverse strandZNF44ZNF563: 12,317,477–12,333,723, reverse strandZNF563ZNF442: 12,345,944–12,365,905, reverse strandZNF442ZNF799: 12,390,016–12,401,280, reverse strandZNF799: 12,391,949–12,441,082, reverse strandZNF443: 12,429,706–12,441,021, reverse strandZNF443: 12,433,103–12,484,816, reverse strandZNF709: 12,461,184–12,513,854, reverse strandZNF709: 12,461,559–12,551,474, reverse strandZNF564: 12,524,903–12,551,542, reverse strandZNF564: 12,525,720–12,580,975, reverse strandZNF490: 12,575,832–12,640,098, reverse strandZNF490ZNF791: 12,610,916–12,633,840, forward strandZNF791MAN2B1: 12,643,831–12,666,762, reverse strand: 12,643,831–12,648,397, reverse strand: 12,664,828–12,669,397, reverse strandWDR83: 12,666,802–12,675,832, forward strandWDR83OS: 12,668,065–12,669,467, reverse strand: 12,668,071–12,681,834, reverse strandDHPS: 12,673,411–12,681,901, reverse strandDHPSFBXW9: 12,687,801–12,696,659, reverse strandFBXW9GNG14: 12,687,998–12,688,422, forward strandGNG14TNPO2: 12,699,201–12,723,932, reverse strandTNPO2TRIR: 12,730,640–12,734,747, reverse strandTRIRGET3: 12,737,139–12,748,325, forward strandGET3BEST2: 12,751,673–12,758,458, forward strandBEST2HOOK2: 12,762,640–12,872,740, reverse strandJUNB: 12,791,486–12,793,315, forward strandJUNBPRDX2: 12,796,817–12,801,882, reverse strandPRDX2THSD8: 12,802,031–12,813,581, forward strandTHSD8RNASEH2A: 12,806,505–12,813,644, forward strandRTBDN: 12,825,477–12,838,362, reverse strandMAST1: 12,833,860–12,874,952, forward strandMAST1DNASE2: 12,875,209–12,881,595, reverse strandDNASE2KLF1: 12,884,405–12,887,201, reverse strandKLF1GCDH: 12,891,128–12,915,261, forward strandGCDHSYCE2: 12,898,786–12,919,306, reverse strandSYCE2FARSA: 12,921,138–12,934,037, reverse strandCALR: 12,938,578–12,944,525, forward strandCALRRAD23A: 12,945,716–12,953,646, forward strandGADD45GIP1: 12,950,701–12,957,333, reverse strandDAND5: 12,965,159–12,974,760, forward strandDAND5NFIX: 12,995,401–13,098,796, forward strandNFIXLYL1: 13,099,028–13,103,188, reverse strandLYL1TRMT1: 13,104,899–13,117,567, reverse strandTRMT1NACC1: 13,116,468–13,141,147, forward strandNACC1STX10: 13,144,058–13,150,383, reverse strandSTX10IER2: 13,150,403–13,156,981, forward strandIER2CACNA1A: 13,206,442–13,624,489, reverse strandCACNA1ADiagram of TNPO2: 26 exons on the reverse strand of chromosome 19Exon 20: 1 known disease-causing siteExon 19: 1 known disease-causing siteExon 16: 1 known disease-causing siteExon 15: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 26: 12,699,201–12,701,243, 2,043 basesExon 25: 12,701,326–12,701,453, 128 basesExon 24: 12,701,598–12,701,672, 75 basesExon 23: 12,701,752–12,701,851, 100 basesExon 22: 12,702,072–12,702,177, 106 basesExon 21: 12,702,823–12,702,918, 96 basesExon 20: 12,703,428–12,703,526, 99 basesExon 19: 12,703,714–12,703,801, 88 basesExon 18: 12,705,240–12,705,398, 159 basesExon 17: 12,705,492–12,705,599, 108 basesExon 16: 12,705,682–12,705,768, 87 basesExon 15: 12,706,196–12,706,367, 172 basesExon 14: 12,706,570–12,706,795, 226 basesExon 13: 12,710,621–12,710,773, 153 basesExon 12: 12,711,296–12,711,461, 166 basesExon 11: 12,711,553–12,711,613, 61 basesExon 10: 12,714,821–12,714,939, 119 basesExon 9: 12,715,047–12,715,169, 123 basesExon 8: 12,715,243–12,715,324, 82 basesExon 7: 12,715,405–12,715,538, 134 basesExon 6: 12,715,633–12,715,739, 107 basesExon 5: 12,719,029–12,719,178, 150 basesExon 4: 12,719,261–12,719,336, 76 basesExon 3: 12,720,879–12,720,990, 112 basesExon 2: 12,723,249–12,723,365, 117 basesExon 1: 12,723,769–12,723,932, 164 bases2625201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.1 kb of the gene's 24.7 kb; 2,694 of those bases code for the protein.

How a genome test reads TNPO2

10

positions in TNPO2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 24.7 kb of TNPO2, introns included, not only the 5.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TNPO2 gene: transportin 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/tnpo2

Vancouver

Dante Labs. TNPO2 gene: transportin 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tnpo2

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