Skip to content
Use your HSA or FSA funds

Gene

NUP214

nucleoporin 214

Summary

Cytogenetic location
9q34.13
Coordinates
Chromosome 9: 131,125,586–131,234,663 (GRCh38)
Exons
36 exons across 109.1 kb
Protein
2,090 amino acids
Also known as
CAIN, CAN, D9S46E, N214
MANE Select transcript
ENST00000359428.10NM_005085.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NUP214 yet. The test sequences your whole genome, so your data includes it all the same.

How NUP214 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 9, with a bracket where NUP214 sits. NUP214 and 17 genes near it on chromosome 9, from 130,680,125 to 131,680,124.Chromosome 99q34.13p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.3130.8 Mb131 Mb131.2 Mb131.4 Mb131.6 MbPRDM12: 130,664,594–130,682,986, forward strandPRDM12EXOSC2: 130,693,721–130,707,608, forward strandEXOSC2ABL1: 130,713,043–130,887,675, forward strandABL1: 130,713,626–130,713,724, forward strandQRFP: 130,892,707–130,896,812, reverse strandQRFPFIBCD1: 130,900,194–130,941,232, reverse strandFIBCD1LAMC3: 131,008,878–131,094,473, forward strandLAMC3AIF1L: 131,096,446–131,123,243, forward strandAIF1LNUP214: 131,125,586–131,234,663, forward strandNUP214FAM78A: 131,258,076–131,278,194, reverse strandFAM78APLPP7: 131,289,459–131,359,022, forward strandPLPP7PRRC2B: 131,373,636–131,500,197, forward strandPRRC2B: 131,430,129–131,430,218, forward strand: 131,432,759–131,446,473, forward strandPOMT1: 131,502,789–131,523,806, forward strandPOMT1UCK1: 131,523,756–131,531,289, reverse strandUCK1PRRT1B: 131,545,520–131,560,893, forward strandPRRT1BRAPGEF1: 131,576,758–131,740,134, reverse strandRAPGEF1Diagram of NUP214: 36 exons on the forward strand of chromosome 9Exon 2: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 1: 131,125,586–131,125,749, 164 basesExon 2: 131,127,524–131,127,719, 196 basesExon 3: 131,128,332–131,128,483, 152 basesExon 4: 131,129,279–131,129,477, 199 basesExon 5: 131,130,766–131,130,836, 71 basesExon 6: 131,132,596–131,132,659, 64 basesExon 7: 131,133,106–131,133,209, 104 basesExon 8: 131,134,898–131,135,004, 107 basesExon 9: 131,135,940–131,136,006, 67 basesExon 10: 131,139,281–131,139,407, 127 basesExon 11: 131,140,549–131,140,710, 162 basesExon 12: 131,144,280–131,144,754, 475 basesExon 13: 131,146,129–131,146,304, 176 basesExon 14: 131,147,490–131,147,584, 95 basesExon 15: 131,150,324–131,150,410, 87 basesExon 16: 131,150,616–131,150,765, 150 basesExon 17: 131,151,736–131,151,894, 159 basesExon 18: 131,159,383–131,159,486, 104 basesExon 19: 131,162,991–131,163,173, 183 basesExon 20: 131,163,870–131,163,955, 86 basesExon 21: 131,164,061–131,164,144, 84 basesExon 22: 131,174,055–131,174,318, 264 basesExon 23: 131,175,460–131,175,621, 162 basesExon 24: 131,178,311–131,178,410, 100 basesExon 25: 131,187,289–131,187,364, 76 basesExon 26: 131,189,053–131,189,131, 79 basesExon 27: 131,192,208–131,192,292, 85 basesExon 28: 131,195,233–131,195,294, 62 basesExon 29: 131,197,216–131,199,015, 1,800 basesExon 30: 131,201,647–131,201,717, 71 basesExon 31: 131,215,212–131,215,368, 157 basesExon 32: 131,222,778–131,222,930, 153 basesExon 33: 131,228,160–131,228,331, 172 basesExon 34: 131,230,630–131,230,769, 140 basesExon 35: 131,232,284–131,232,308, 25 basesExon 36: 131,233,454–131,234,663, 1,210 bases1246810121416182022242628303234365′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.6 kb of the gene's 109.1 kb; 6,273 of those bases code for the protein.

How a genome test reads NUP214

2

positions in NUP214 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 109.1 kb of NUP214, introns included, not only the 7.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NUP214 gene: nucleoporin 214. Retrieved 16 October 2026, from https://dantelabs.com/genes/nup214

Vancouver

Dante Labs. NUP214 gene: nucleoporin 214 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/nup214

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test