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Gene

MBOAT7

membrane bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

Summary

Cytogenetic location
19q13.42
Coordinates
Chromosome 19: 54,173,415–54,189,580 (GRCh38)
Exons
8 exons across 16.2 kb
Protein
472 amino acids
Also known as
BB1, hMBOA-7, LPLAT, LPIAT1, LPLAT11
Previous symbols
LENG4
MANE Select transcript
ENST00000245615.6NM_024298.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    How MBOAT7 is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Known disease-causing sites
    • Stretches short reads find hard
    Chromosome 19, with a bracket where MBOAT7 sits. MBOAT7 and 33 genes near it on chromosome 19, from 53,681,498 to 54,681,497.Chromosome 1919q13.42p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4353.8 Mb54 Mb54.2 Mb54.4 Mb54.6 MbNLRP12: 53,792,139–53,824,403, reverse strandNLRP12MYADM: 53,864,763–53,878,125, forward strandMYADMPRKCG: 53,879,190–53,907,652, forward strandPRKCGCACNG7: 53,909,264–53,943,950, forward strandCACNG7CACNG8: 53,962,937–53,990,215, forward strandCACNG8CACNG6: 53,991,605–54,012,670, forward strandCACNG6VSTM1: 54,040,825–54,063,959, reverse strandVSTM1TARM1: 54,069,895–54,081,365, reverse strandOSCAR: 54,094,668–54,102,692, reverse strandOSCARNDUFA3: 54,102,728–54,111,522, forward strandTFPT: 54,107,015–54,115,666, reverse strandTFPTPRPF31: 54,115,410–54,131,719, forward strandPRPF31CNOT3: 54,137,710–54,155,708, forward strandLENG1: 54,155,161–54,159,760, reverse strandLENG1TMC4: 54,160,095–54,173,250, reverse strandTMC4MBOAT7: 54,173,415–54,189,580, reverse strandMBOAT7TSEN34: 54,188,464–54,194,538, forward strandTSEN34RPS9: 54,200,466–54,249,003, forward strandRPS9LILRB3: 54,215,940–54,223,506, reverse strandLILRB3LILRA6: 54,236,590–54,242,820, reverse strandLILRB5: 54,249,421–54,257,339, reverse strandLILRB5LILRB2: 54,273,812–54,281,184, reverse strandLILRA5: 54,307,037–54,313,177, reverse strandLILRA5LILRA4: 54,333,185–54,339,162, reverse strandLILRA4LAIR1: 54,351,384–54,370,558, reverse strandLAIR1TTYH1: 54,415,219–54,436,904, forward strandTTYH1LENG8: 54,449,157–54,462,022, forward strandLENG8LENG9: 54,461,732–54,463,778, reverse strandLENG9CDC42EP5: 54,465,026–54,473,316, reverse strandCDC42EP5LAIR2: 54,497,879–54,510,694, forward strandLAIR2LILRA2: 54,572,920–54,590,287, forward strandLILRA2LILRA1: 54,593,582–54,603,259, forward strandLILRA1LILRB1: 54,616,309–54,638,022, forward strandLILRB1LILRB4: 54,643,889–54,670,531, forward strandLILRB4Diagram of MBOAT7: 8 exons on the reverse strand of chromosome 19Exon 8: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 6: 3 known disease-causing sitesExon 5: 1 known disease-causing siteExon 3: 2 known disease-causing sitesExon 2: 1 known disease-causing siteExon 8: 54,173,415–54,174,431, 1,017 basesExon 7: 54,178,765–54,178,941, 177 basesExon 6: 54,180,773–54,181,133, 361 basesExon 5: 54,183,521–54,183,680, 160 basesExon 4: 54,187,161–54,187,287, 127 basesExon 3: 54,188,217–54,188,346, 130 basesExon 2: 54,188,433–54,188,511, 79 basesExon 1: 54,189,338–54,189,580, 243 bases864215′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 2.3 kb of the gene's 16.2 kb; 1,419 of those bases code for the protein.

    How a genome test reads MBOAT7

    12

    positions in MBOAT7 where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    A whole genome covers all 16.2 kb of MBOAT7, introns included, not only the 2.3 kb of exons.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). MBOAT7 gene: membrane bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7. Retrieved 16 October 2026, from https://dantelabs.com/genes/mboat7

    Vancouver

    Dante Labs. MBOAT7 gene: membrane bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/mboat7

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