Trait
Peripheral arterial stenosis
Narrowing of peripheral arteries with reduction of blood flow to the limbs. This feature may be quantified as an ankle-brachial index of less than 0.9, and may be manifested clinically as claudication.
Summary
- Also called
- Peripheral artery disease
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Peripheral arterial stenosis, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test32 genes linked to Peripheral arterial stenosis
Changes in these genes cause rare conditions in which Peripheral arterial stenosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| LMNAlamin A/C | Very often (80–99%) | In 1 condition |
| ABCG5ATP binding cassette subfamily G member 5 | Often (30–79%) | In 1 condition |
| ABCG8ATP binding cassette subfamily G member 8 | Often (30–79%) | In 1 condition |
| APOBapolipoprotein B | Often (30–79%) | In 1 condition |
| JAK2Janus kinase 2 | Often (30–79%) | In 1 condition |
| LDLRlow density lipoprotein receptor | Often (30–79%) | In 1 condition |
| LDLRAP1low density lipoprotein receptor adaptor protein 1 | Often (30–79%) | In 1 condition |
| MPLMPL proto-oncogene, thrombopoietin receptor | Often (30–79%) | In 1 condition |
| PCSK9proprotein convertase subtilisin/kexin type 9 | Often (30–79%) | In 1 condition |
| THPOthrombopoietin | Often (30–79%) | In 1 condition |
| ACTA2actin alpha 2, smooth muscle | Sometimes (5–29%) | In 1 condition |
| APOEapolipoprotein E | Sometimes (5–29%) | In 2 conditions |
| EFEMP2EGF-like fibulin extracellular matrix protein 2 | Sometimes (5–29%) | In 1 condition |
| ELNelastin | Sometimes (5–29%) | In 2 conditions |
| FBN1fibrillin 1 | Sometimes (5–29%) | In 1 condition |
| FOXE3forkhead box E3 | Sometimes (5–29%) | In 1 condition |
| HEY2hes related family bHLH transcription factor with YRPW motif 2 | Sometimes (5–29%) | In 1 condition |
| LOXlysyl oxidase | Sometimes (5–29%) | In 1 condition |
| MAT2Amethionine adenosyltransferase 2A | Sometimes (5–29%) | In 1 condition |
| MFAP5microfibril associated protein 5 | Sometimes (5–29%) | In 1 condition |
| MYH11myosin heavy chain 11 | Sometimes (5–29%) | In 2 conditions |
| MYLKmyosin light chain kinase | Sometimes (5–29%) | In 1 condition |
| PRKG1protein kinase cGMP-dependent 1 | Sometimes (5–29%) | In 1 condition |
| SMAD2SMAD family member 2 | Sometimes (5–29%) | In 1 condition |
| SMAD3SMAD family member 3 | Sometimes (5–29%) | In 1 condition |
| SMAD4SMAD family member 4 | Sometimes (5–29%) | In 1 condition |
| TGFB2transforming growth factor beta 2 | Sometimes (5–29%) | In 1 condition |
| TGFB3transforming growth factor beta 3 | Sometimes (5–29%) | In 1 condition |
| TGFBR1transforming growth factor beta receptor 1 | Sometimes (5–29%) | In 1 condition |
| TGFBR2transforming growth factor beta receptor 2 | Sometimes (5–29%) | In 1 condition |
| THSD4thrombospondin type 1 domain containing 4 | Sometimes (5–29%) | In 1 condition |
| AGXTalanine--glyoxylate aminotransferase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks