Gene
CHD5
chromodomain helicase DNA binding protein 5
- HGNC 16816(opens in a new tab)
- Ensembl gene ENSG00000116254(opens in a new tab)
- NCBI Gene 26038(opens in a new tab)
Summary
- Cytogenetic location
- 1p36.31
- Coordinates
- Chromosome 1: 6,101,787–6,180,321 (GRCh38)
- Exons
- 42 exons across 78.5 kb
- Protein
- 1,954 amino acids
- MANE Select transcript
- ENST00000262450.8NM_015557.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads CHD5 yet. The test sequences your whole genome, so your data includes it all the same.
How CHD5 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 9.9 kb of the gene's 78.5 kb; 5,865 of those bases code for the protein.
How a genome test reads CHD5
21
positions in CHD5 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 78.5 kb of CHD5, introns included, not only the 9.9 kb of exons.
Traits linked to CHD5
The Human Phenotype Ontology lists these as features of the rare conditions CHD5 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Delayed speech and language development
- Autism spectrum disorder
- Epilepsy
- Intellectual disability
- Motor delay
- Aggressive behavior
- Attention deficit
- Obsessive compulsive behavior
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). CHD5 gene: chromodomain helicase DNA binding protein 5. Retrieved 16 October 2026, from https://dantelabs.com/genes/chd5
Dante Labs. CHD5 gene: chromodomain helicase DNA binding protein 5 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/chd5
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