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Traits
Traits linked to ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13
The Human Phenotype Ontology links 20 traits to ADAMTS13, by body system: features seen in people with one of the gene's rare conditions.
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Laboratory abnormality
| Trait | How often it is seen |
|---|---|
| Elevated creatinine | Not recorded |
| Fever | Not recorded |
| High urine protein levels | Not recorded |
| Higher than normal levels of lactate in blood | Not recorded |
| Increased blood urea nitrogen | Not recorded |
| Small amount of blood in urine | Not recorded |
Abnormality of blood and blood-forming tissues
| Trait | How often it is seen |
|---|---|
| Increased immature red blood cells | Not recorded |
| Low platelet count | Not recorded |
| Microangiopathic hemolytic anemia | Not recorded |
| Schistocytosis | Not recorded |
Abnormality of the cardiovascular system
| Trait | How often it is seen |
|---|---|
| Mini stroke | Sometimes (5–29%) |
| Stroke | Sometimes (5–29%) |
| Heart attack | Rarely (1–4%) |
Abnormality of the digestive system
| Trait | How often it is seen |
|---|---|
| Jaundice | Often (30–79%) |
| Prolonged yellowing of skin in newborn | Not recorded |
Abnormality of the genitourinary system
| Trait | How often it is seen |
|---|---|
| Abnormal kidney function | Not recorded |
| Hemolytic-uremic syndrome | Not recorded |
Abnormality of the nervous system
Abnormality of the respiratory system
| Trait | How often it is seen |
|---|---|
| Breathing difficulties | Sometimes (5–29%) |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to ADAMTS13 and how often each is seen. Find out more at hpo.jax.org.
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