Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
Trait
Increased mean corpuscular volume
Larger than normal size of erythrocytes.
Summary
- Also called
- Erythrocyte macrocytosis, Increased MCV
Increased mean corpuscular volumeHP:0005518
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
Read the genes linked to Increased mean corpuscular volume, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test55 genes linked to Increased mean corpuscular volume
Changes in these genes cause rare conditions in which Increased mean corpuscular volume is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DHFRdihydrofolate reductase | Always | In 1 condition |
| ETV6ETS variant transcription factor 6 | Always | In 1 condition |
| FAAP100FA core complex associated protein 100 | Always | In 1 condition |
| LARS2leucyl-tRNA synthetase 2, mitochondrial | Always | In 1 condition |
| LIG1DNA ligase 1 | Always | In 1 condition |
| MMADHCmetabolism of cobalamin associated D | Always | In 2 conditions |
| POT1protection of telomeres 1 | Always | In 1 condition |
| RPL17ribosomal protein L17 | Always | In 1 condition |
| RPS7ribosomal protein S7 | Always | In 2 conditions |
| TSR2TSR2 ribosome maturation factor | Always | In 2 conditions |
| RPS19ribosomal protein S19 | Very often (80–99%) | In 2 conditions |
| TERCtelomerase RNA component | Very often (80–99%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Very often (80–99%) | In 1 condition |
| TINF2TERF1 interacting nuclear factor 2 | Very often (80–99%) | In 1 condition |
| ADA2adenosine deaminase 2 | Often (30–79%) | In 1 condition |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Often (30–79%) | In 2 conditions |
| DUTdeoxyuridine triphosphatase | Often (30–79%) | In 1 condition |
| EFL1elongation factor like GTPase 1 | Often (30–79%) | In 1 condition |
| GATA1GATA binding protein 1 | Often (30–79%) | In 1 condition |
| HEATR3HEAT repeat containing 3 | Often (30–79%) | In 1 condition |
| KIF23kinesin family member 23 | Often (30–79%) | In 1 condition |
| MDM4MDM4 regulator of p53 | Often (30–79%) | In 1 condition |
| MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase | Often (30–79%) | In 1 condition |
| RACGAP1Rac GTPase activating protein 1 | Often (30–79%) | In 1 condition |
| RPL11ribosomal protein L11 | Often (30–79%) | In 2 conditions |
| RPL15ribosomal protein L15 | Often (30–79%) | In 1 condition |
| RPL18ribosomal protein L18 | Often (30–79%) | In 1 condition |
| RPL26ribosomal protein L26 | Often (30–79%) | In 1 condition |
| RPL27ribosomal protein L27 | Often (30–79%) | In 1 condition |
| RPL31ribosomal protein L31 | Often (30–79%) | In 1 condition |
| RPL35ribosomal protein L35 | Often (30–79%) | In 1 condition |
| RPL35Aribosomal protein L35a | Often (30–79%) | In 1 condition |
| RPL5ribosomal protein L5 | Often (30–79%) | In 2 conditions |
| RPL8ribosomal protein L8 | Often (30–79%) | In 1 condition |
| RPL9ribosomal protein L9 | Often (30–79%) | In 1 condition |
| RPS10ribosomal protein S10 | Often (30–79%) | In 1 condition |
| RPS15Aribosomal protein S15a | Often (30–79%) | In 1 condition |
| RPS17ribosomal protein S17 | Often (30–79%) | In 1 condition |
| RPS20ribosomal protein S20 | Often (30–79%) | In 1 condition |
| RPS24ribosomal protein S24 | Often (30–79%) | In 2 conditions |
Show 15 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| RPS26ribosomal protein S26 | Often (30–79%) | In 1 condition |
| RPS27ribosomal protein S27 | Often (30–79%) | In 1 condition |
| RPS28ribosomal protein S28 | Often (30–79%) | In 1 condition |
| RPS29ribosomal protein S29 | Often (30–79%) | In 1 condition |
| SBDSSBDS ribosome maturation factor | Often (30–79%) | In 1 condition |
| ABCB6ATP binding cassette subfamily B member 6 (LAN blood group) | Sometimes (5–29%) | In 1 condition |
| ANKRD11ankyrin repeat domain 11 | Sometimes (5–29%) | In 1 condition |
| KCNN4potassium calcium-activated channel subfamily N member 4 | Sometimes (5–29%) | In 2 conditions |
| PIEZO1piezo type mechanosensitive ion channel component 1 (Er blood group) | Sometimes (5–29%) | In 1 condition |
| RHAGRh associated glycoprotein | Sometimes (5–29%) | In 1 condition |
| SLC4A1solute carrier family 4 member 1 (Diego blood group) | Sometimes (5–29%) | In 2 conditions |
| HBBhemoglobin subunit beta | Rarely (1–4%) | In 1 condition |
| CBLIFcobalamin binding intrinsic factor | Not recorded | In 1 condition |
| SAMD9sterile alpha motif domain containing 9 | Not recorded | In 1 condition |
| SAMD9Lsterile alpha motif domain containing 9 like | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Who We HelpOur ScienceProductsOutcomes
Log InAskGet Startedfrom $449
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks