Trait
Talipes valgus
Outward turning of the heel, resulting in clubfoot with the person walking on the inner part of the foot.
Summary
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test23 genes linked to Talipes valgus
Changes in these genes cause rare conditions in which Talipes valgus is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DNMT3ADNA methyltransferase 3 alpha | Always | In 1 condition |
| HNRNPH1heterogeneous nuclear ribonucleoprotein H1 | Always | In 1 condition |
| RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2 | Always | In 1 condition |
| CARS1cysteinyl-tRNA synthetase 1 | Sometimes (5–29%) | In 1 condition |
| CHMP1Acharged multivesicular body protein 1A | Sometimes (5–29%) | In 1 condition |
| MAN2B1mannosidase alpha class 2B member 1 | Sometimes (5–29%) | In 1 condition |
| NONOnon-POU domain containing octamer binding | Sometimes (5–29%) | In 1 condition |
| ADGRV1adhesion G protein-coupled receptor V1 | Rarely (1–4%) | In 1 condition |
| CPA6carboxypeptidase A6 | Rarely (1–4%) | In 1 condition |
| EXT1exostosin glycosyltransferase 1 | Rarely (1–4%) | In 1 condition |
| EXT2exostosin glycosyltransferase 2 | Rarely (1–4%) | In 1 condition |
| FGF13fibroblast growth factor 13 | Rarely (1–4%) | In 1 condition |
| GABRDgamma-aminobutyric acid type A receptor subunit delta | Rarely (1–4%) | In 1 condition |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Rarely (1–4%) | In 1 condition |
| HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1 | Rarely (1–4%) | In 1 condition |
| PRRT2proline rich transmembrane protein 2 | Rarely (1–4%) | In 1 condition |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Rarely (1–4%) | In 1 condition |
| SCN1Bsodium voltage-gated channel beta subunit 1 | Rarely (1–4%) | In 1 condition |
| SCN2Asodium voltage-gated channel alpha subunit 2 | Rarely (1–4%) | In 1 condition |
| SCN9Asodium voltage-gated channel alpha subunit 9 | Rarely (1–4%) | In 1 condition |
| SLC32A1solute carrier family 32 member 1 | Rarely (1–4%) | In 1 condition |
| STX1Bsyntaxin 1B | Rarely (1–4%) | In 1 condition |
| LIFRLIF receptor subunit alpha | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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