Traits

Traits linked to WHRN

whirlin

The Human Phenotype Ontology links 22 traits to WHRN, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the eye

Trait	How often it is seen
Difficulties with night vision	Always
Rod-cone dystrophy	Always
Abnormal electroretinogram	Very often (80–99%)
Blind spot	Very often (80–99%)
Light eye color	Very often (80–99%)
Visual loss	Very often (80–99%)
Close sighted	Often (30–79%)
Clouding of the lens of the eye	Often (30–79%)
Decreased clarity of vision	Often (30–79%)
Limited peripheral vision	Often (30–79%)
Loss of peripheral vision	Often (30–79%)
Abnormal color vision	Sometimes (5–29%)
Reduced contrast sensitivity	Sometimes (5–29%)

Abnormality of the ear

Trait	How often it is seen
Hearing impairment	Always
Sensorineural hearing impairment	Always
Abnormality of the inner ear	Very often (80–99%)
Abnormal vestibular function	Rarely (1–4%)

Abnormality of the nervous system

Trait	How often it is seen
Difficulty sleeping	Often (30–79%)
Abnormality of balance	Sometimes (5–29%)
Anxiety	Sometimes (5–29%)
Depression	Sometimes (5–29%)

Constitutional symptom

Trait	How often it is seen
Fatigue	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to WHRN and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test