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Gene

SLC2A9

solute carrier family 2 member 9

Summary

Cytogenetic location
4p16.1
Coordinates
Chromosome 4: 9,826,224–10,021,497 (GRCh38)
Exons
12 exons across 195.3 kb
Protein
540 amino acids
Inheritance
Autosomal recessive
Also known as
Glut9, GLUTX, URATv1
MANE Select transcript
ENST00000264784.8NM_020041.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Renal Hypouricemia

    • Hereditary Renal HypouricemiaAutosomal recessive

      A recessive disorder of uric acid reabsorption caused by variants in SLC22A12 or SLC2A9, associated with exercise-induced acute kidney injury and uric acid stones.

      • 2 GenCC submitters rate it definitive or strong
      What knowing changes

      Knowing supports staying well hydrated and avoiding extreme anaerobic exercise to reduce the risk of kidney injury.

Inheritance

Autosomal recessive
It takes a changed copy from each parent. With one, you are a carrier and usually unaffected; when both parents are carriers, each child has a one-in-four chance of inheriting two.

How SLC2A9 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 4, with a bracket where SLC2A9 sits. SLC2A9 and 3 genes near it on chromosome 4, from 9,423,861 to 10,423,860.Chromosome 44p16.1p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.29.6 Mb9.8 Mb10 Mb10.2 Mb10.4 MbDEFB131A: 9,444,413–9,450,672, forward strandDEFB131ADRD5: 9,781,387–9,784,012, forward strandDRD5SLC2A9: 9,826,224–10,021,497, reverse strandSLC2A9WDR1: 10,068,089–10,116,988, reverse strandWDR1Diagram of SLC2A9: 12 exons on the reverse strand of chromosome 4Exon 12: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 3: 2 known disease-causing sitesExon 2: 1 known disease-causing siteExon 12: 9,826,224–9,826,600, 377 basesExon 11: 9,834,881–9,835,008, 128 basesExon 10: 9,887,567–9,887,642, 76 basesExon 9: 9,890,610–9,890,711, 102 basesExon 8: 9,908,235–9,908,345, 111 basesExon 7: 9,920,385–9,920,572, 188 basesExon 6: 9,941,913–9,942,045, 133 basesExon 5: 9,980,592–9,980,737, 146 basesExon 4: 9,985,669–9,985,793, 125 basesExon 3: 9,996,781–9,996,941, 161 basesExon 2: 10,018,975–10,019,073, 99 basesExon 1: 10,021,280–10,021,497, 218 bases1210515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.9 kb of the gene's 195.3 kb; 1,623 of those bases code for the protein.

How a genome test reads SLC2A9

7

positions in SLC2A9 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 195.3 kb of SLC2A9, introns included, not only the 1.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SLC2A9 gene: solute carrier family 2 member 9. Retrieved 17 October 2026, from https://dantelabs.com/genes/slc2a9

Vancouver

Dante Labs. SLC2A9 gene: solute carrier family 2 member 9 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/slc2a9

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