Trait

Medulloblastoma

A rapidly growing embryonic tumor arising in the posterior part of the cerebellar vermis and neuroepithelial roof of the fourth ventricle in children. More rarely, medulloblastoma arises in the cerebellum in adults.

HPO HP:0002885

Body system: Abnormality of the nervous system Abnormal tissue mass

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/medulloblastoma.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

Read the genes linked to Medulloblastoma, and the rest of your genome, with one test.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test

18 genes linked to Medulloblastoma

Changes in these genes cause rare conditions in which Medulloblastoma is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
PTCH1patched 1	Very often (80–99%)	In 3 conditions
PALB2partner and localizer of BRCA2	Often (30–79%)	In 1 condition
SUFUSUFU negative regulator of hedgehog signaling	Often (30–79%)	In 3 conditions
BRCA2BRCA2 DNA repair associated	Sometimes (5–29%)	In 2 conditions
APCAPC regulator of Wnt signaling pathway	Rarely (1–4%)	In 2 conditions
ASXL1ASXL transcriptional regulator 1	Rarely (1–4%)	In 1 condition
CDKN2Acyclin dependent kinase inhibitor 2A	Rarely (1–4%)	In 1 condition
CHEK2checkpoint kinase 2	Rarely (1–4%)	In 1 condition
DICER1dicer 1, ribonuclease III	Rarely (1–4%)	In 1 condition
MDM2MDM2 proto-oncogene	Rarely (1–4%)	In 1 condition
PTCH2patched 2	Rarely (1–4%)	In 2 conditions
TP53tumor protein p53	Rarely (1–4%)	In 1 condition
CTNNB1catenin beta 1	Not recorded	In 1 condition
ELP1elongator acetyltransferase complex subunit 1	Not recorded	In 1 condition
GPR161G protein-coupled receptor 161	Not recorded	In 1 condition
MLH1mutL homolog 1	Not recorded	In 1 condition
NBNnibrin	Not recorded	In 1 condition
SMARCB1SWI/SNF related BAF chromatin remodeling complex subunit B1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Cerebellar medulloblastoma2 genes

Broader traits

Malignant neoplasm of the central nervous system

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

One test. A lifetime of answers.