Traits

Traits linked to SOBP

sine oculis binding protein homolog

The Human Phenotype Ontology links 15 traits to SOBP, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	How often it is seen
Intellectual disability, severe	Always
Short attention span	Often (30–79%)
Psychosis	Sometimes (5–29%)
Delayed speech and language development	Not recorded
Global developmental delay	Not recorded
Poor speech	Not recorded

Abnormality of the eye

Trait	How often it is seen
Cross-eyed	Very often (80–99%)
Inward turning cross eyed	Very often (80–99%)
Farsightedness	Sometimes (5–29%)
Lazy eye	Sometimes (5–29%)
Visual impairment	Sometimes (5–29%)

Abnormality of head or neck

Trait	How often it is seen
Big maxilla	Very often (80–99%)
Dental crowding	Very often (80–99%)
Open bite	Very often (80–99%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Double-Jointed	Always

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to SOBP and how often each is seen. Find out more at hpo.jax.org.

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