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Gene

SMARCA5

SNF2 related chromatin remodeling ATPase 5

Summary

Cytogenetic location
4q31.21
Coordinates
Chromosome 4: 143,513,702–143,557,486 (GRCh38)
Exons
24 exons across 43.8 kb
Protein
1,052 amino acids
Also known as
hSNF2H, hISWI, ISWI
MANE Select transcript
ENST00000283131.4NM_003601.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMARCA5 yet. The test sequences your whole genome, so your data includes it all the same.

How SMARCA5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 4, with a bracket where SMARCA5 sits. SMARCA5 and 5 genes near it on chromosome 4, from 143,035,594 to 144,035,593.Chromosome 44q31.21p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.2143.2 Mb143.4 Mb143.6 Mb143.8 Mb144 MbUSP38: 143,184,917–143,228,233, forward strandUSP38GAB1: 143,336,150–143,474,565, forward strandGAB1SMARCA5: 143,513,702–143,557,486, forward strandSMARCA5FREM3: 143,577,302–143,700,675, reverse strandFREM3GYPE: 143,832,835–143,905,563, reverse strandGYPEGYPB: 143,983,268–144,019,380, reverse strandGYPBDiagram of SMARCA5: 24 exons on the forward strand of chromosome 4Exon 21: 1 known disease-causing siteExon 1: 143,513,702–143,514,101, 400 basesExon 2: 143,517,355–143,517,429, 75 basesExon 3: 143,521,429–143,521,595, 167 basesExon 4: 143,524,367–143,524,467, 101 basesExon 5: 143,525,451–143,525,551, 101 basesExon 6: 143,526,281–143,526,460, 180 basesExon 7: 143,527,868–143,528,023, 156 basesExon 8: 143,528,583–143,528,714, 132 basesExon 9: 143,530,458–143,530,526, 69 basesExon 10: 143,534,855–143,534,964, 110 basesExon 11: 143,536,452–143,536,678, 227 basesExon 12: 143,538,590–143,538,711, 122 basesExon 13: 143,538,786–143,538,938, 153 basesExon 14: 143,540,363–143,540,495, 133 basesExon 15: 143,543,509–143,543,657, 149 basesExon 16: 143,543,853–143,543,972, 120 basesExon 17: 143,544,737–143,544,847, 111 basesExon 18: 143,545,470–143,545,583, 114 basesExon 19: 143,545,925–143,546,047, 123 basesExon 20: 143,546,776–143,546,908, 133 basesExon 21: 143,547,385–143,547,503, 119 basesExon 22: 143,547,928–143,548,140, 213 basesExon 23: 143,549,997–143,550,104, 108 basesExon 24: 143,553,119–143,557,486, 4,368 bases1246810121416182022245′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.7 kb of the gene's 43.8 kb; 3,159 of those bases code for the protein.

How a genome test reads SMARCA5

1

position in SMARCA5 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 43.8 kb of SMARCA5, introns included, not only the 7.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SMARCA5 gene: SNF2 related chromatin remodeling ATPase 5. Retrieved 17 October 2026, from https://dantelabs.com/genes/smarca5

Vancouver

Dante Labs. SMARCA5 gene: SNF2 related chromatin remodeling ATPase 5 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smarca5

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