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Gene

RELT

RELT TNF receptor

Summary

Cytogenetic location
11q13.4
Coordinates
Chromosome 11: 73,376,399–73,397,474 (GRCh38)
Exons
11 exons across 21.1 kb
Protein
430 amino acids
Inheritance
Autosomal dominant
Also known as
FLJ14993
Previous symbols
TNFRSF19L
MANE Select transcript
ENST00000064780.7NM_152222.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

Inheritance

Autosomal dominant
One changed copy, from either parent, is enough. A parent who has one passes it on to each child with a one-in-two chance.

How RELT is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 11, with a bracket where RELT sits. RELT and 10 genes near it on chromosome 11, from 72,886,937 to 73,886,936.Chromosome 1111q13.4p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2573 Mb73.2 Mb73.4 Mb73.6 Mb73.8 MbFCHSD2: 72,836,042–73,142,485, reverse strandFCHSD2P2RY2: 73,216,664–73,242,427, forward strandP2RY2P2RY6: 73,264,498–73,305,103, forward strandP2RY6ARHGEF17: 73,308,276–73,370,786, forward strandARHGEF17RELT: 73,376,399–73,397,474, forward strandRELTFAM168A: 73,400,487–73,598,253, reverse strandFAM168APLEKHB1: 73,646,178–73,662,819, forward strandPLEKHB1RAB6A: 73,675,638–73,761,465, reverse strandRAB6AMRPL48: 73,787,297–73,865,653, forward strandMRPL48COA4: 73,869,846–73,876,982, reverse strandCOA4PAAF1: 73,876,699–73,931,128, forward strandPAAF1Diagram of RELT: 11 exons on the forward strand of chromosome 11Exon 4: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 1: 73,376,399–73,376,499, 101 basesExon 2: 73,389,112–73,389,181, 70 basesExon 3: 73,390,551–73,390,625, 75 basesExon 4: 73,390,755–73,390,921, 167 basesExon 5: 73,391,144–73,391,223, 80 basesExon 6: 73,392,211–73,392,468, 258 basesExon 7: 73,393,837–73,393,917, 81 basesExon 8: 73,394,236–73,394,317, 82 basesExon 9: 73,394,477–73,394,734, 258 basesExon 10: 73,395,087–73,395,285, 199 basesExon 11: 73,395,444–73,397,474, 2,031 bases1246810115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.4 kb of the gene's 21.1 kb; 1,293 of those bases code for the protein.

How a genome test reads RELT

3

positions in RELT where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 21.1 kb of RELT, introns included, not only the 3.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RELT gene: RELT TNF receptor. Retrieved 16 October 2026, from https://dantelabs.com/genes/relt

Vancouver

Dante Labs. RELT gene: RELT TNF receptor [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/relt

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