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Gene

PLEKHB1

pleckstrin homology domain containing B1

Summary

Cytogenetic location
11q13.4
Coordinates
Chromosome 11: 73,646,581–73,662,819 (GRCh38)
Exons
8 exons across 16.2 kb
Protein
243 amino acids
Also known as
PHR1, KPL1
Previous symbols
PHRET1
MANE Select transcript
ENST00000354190.10NM_021200.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PLEKHB1 yet. The test sequences your whole genome, so your data includes it all the same.

How PLEKHB1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 11, with a bracket where PLEKHB1 sits. PLEKHB1 and 13 genes near it on chromosome 11, from 73,154,700 to 74,154,699.Chromosome 1111q13.4p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2573.2 Mb73.4 Mb73.6 Mb73.8 Mb74 MbP2RY2: 73,216,664–73,242,427, forward strandP2RY2P2RY6: 73,264,498–73,305,103, forward strandP2RY6ARHGEF17: 73,308,276–73,370,786, forward strandARHGEF17RELT: 73,376,325–73,397,474, forward strandRELTFAM168A: 73,400,487–73,598,253, reverse strandFAM168APLEKHB1: 73,646,581–73,662,819, forward strandPLEKHB1RAB6A: 73,675,638–73,761,465, reverse strandRAB6AMRPL48: 73,787,297–73,865,653, forward strandMRPL48COA4: 73,869,846–73,876,982, reverse strandCOA4PAAF1: 73,876,699–73,931,128, forward strandPAAF1DNAJB13: 73,951,014–73,970,366, forward strandDNAJB13UCP2: 73,973,431–73,983,542, reverse strandUCP2UCP3: 74,000,277–74,009,241, reverse strandUCP3C2CD3: 74,012,718–74,171,210, reverse strandC2CD3Diagram of PLEKHB1: 8 exons on the forward strand of chromosome 11Exon 1: 73,646,581–73,646,626, 46 basesExon 2: 73,649,012–73,649,087, 76 basesExon 3: 73,650,553–73,650,705, 153 basesExon 4: 73,651,788–73,651,890, 103 basesExon 5: 73,652,975–73,653,014, 40 basesExon 6: 73,655,803–73,655,907, 105 basesExon 7: 73,660,753–73,660,852, 100 basesExon 8: 73,661,466–73,662,819, 1,354 bases123456785′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 16.2 kb; 732 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PLEKHB1 gene: pleckstrin homology domain containing B1. Retrieved 17 October 2026, from https://dantelabs.com/genes/plekhb1

Vancouver

Dante Labs. PLEKHB1 gene: pleckstrin homology domain containing B1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/plekhb1

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