Gene
ODAPH
odontogenesis associated phosphoprotein
- HGNC 26300↗(opens in a new tab)
- Ensembl gene ENSG00000174792↗(opens in a new tab)
- NCBI Gene 152816↗(opens in a new tab)
Summary
- Cytogenetic location
- 4q21.1
- Coordinates
- Chromosome 4: 75,556,066–75,564,817 (GRCh38)
- Exons
- 2 exons across 8.8 kb
- Protein
- 130 amino acids
- Inheritance
- Autosomal dominant
- Also known as
- FLJ23657, AI2A4
- Previous symbols
- C4orf26
- MANE Select transcript
- ENST00000311623.9NM_178497.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Amelogenesis Imperfecta
- Autosomal dominant
- 2 GenCC submitters rate it definitive or strong
Inheritance
- Autosomal dominant
- One changed copy, from either parent, is enough. A parent who has one passes it on to each child with a one-in-two chance.
How ODAPH is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 0.8 kb of the gene's 8.8 kb; 393 of those bases code for the protein.
How a genome test reads ODAPH
1
position in ODAPH where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 8.8 kb of ODAPH, introns included, not only the 0.8 kb of exons.
Genes linked to the same conditions
- ACP4acid phosphatase 4Shares 1 condition
- AMBNameloblastinShares 1 condition
- AMELXamelogenin X-linkedShares 1 condition
- DLX3distal-less homeobox 3Shares 1 condition
- ENAMenamelinShares 1 condition
- FAM20AFAM20A golgi associated secretory pathway pseudokinaseShares 1 condition
- GPR68G protein-coupled receptor 68Shares 1 condition
- ITGB6integrin subunit beta 6Shares 1 condition
- KLK4kallikrein related peptidase 4Shares 1 condition
- LAMB3laminin subunit beta 3Shares 1 condition
- MMP20matrix metallopeptidase 20Shares 1 condition
- RELTRELT TNF receptorShares 1 condition
Traits linked to ODAPH
The Human Phenotype Ontology lists these as features of the rare conditions ODAPH can cause. Each trait's page lists the other genes linked to it.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
- The ACMG secondary findings list, SF v3.2.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). ODAPH gene: odontogenesis associated phosphoprotein. Retrieved 16 October 2026, from https://dantelabs.com/genes/odaph
Dante Labs. ODAPH gene: odontogenesis associated phosphoprotein [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/odaph
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