Gene
KIF5C
kinesin family member 5C
- HGNC 6325↗(opens in a new tab)
- Ensembl gene ENSG00000168280↗(opens in a new tab)
- NCBI Gene 3800↗(opens in a new tab)
Summary
- Cytogenetic location
- 2q23.1-q23.2
- Coordinates
- Chromosome 2: 148,875,227–149,026,759 (GRCh38)
- Exons
- 26 exons across 151.5 kb
- Protein
- 957 amino acids
- Also known as
- NKHC2
- MANE Select transcript
- ENST00000435030.6NM_004522.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads KIF5C yet. The test sequences your whole genome, so your data includes it all the same.
How KIF5C is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 7 kb of the gene's 151.5 kb; 2,874 of those bases code for the protein.
How a genome test reads KIF5C
10
positions in KIF5C where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 151.5 kb of KIF5C, introns included, not only the 7 kb of exons.
Traits linked to KIF5C
The Human Phenotype Ontology lists these as features of the rare conditions KIF5C can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Absent speech development
- Clonic seizure
- Epilepsy
- Intellectual disability, severe
- More grooves in brain
- Repetitive movements
- Self-injurious behavior
- Underdevelopment of part of brain called corpus callosum
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). KIF5C gene: kinesin family member 5C. Retrieved 16 October 2026, from https://dantelabs.com/genes/kif5c
Dante Labs. KIF5C gene: kinesin family member 5C [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/kif5c
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