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Gene

DNAH6

dynein axonemal heavy chain 6

Summary

Cytogenetic location
2p11.2
Coordinates
Chromosome 2: 84,516,498–84,819,589 (GRCh38)
Exons
77 exons across 303.1 kb
Protein
4,158 amino acids
Also known as
Dnahc6, HL-2, FLJ37357
Previous symbols
DNHL1
MANE Select transcript
ENST00000389394.8NM_001370.2
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Male Infertility

    • The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

      • ClinGen rates the link strong
      • 2 GenCC submitters rate it definitive or strong

How DNAH6 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where DNAH6 sits. DNAH6 and 5 genes near it on chromosome 2, from 84,168,044 to 85,168,043.Chromosome 22p11.2p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.384.2 Mb84.4 Mb84.6 Mb84.8 Mb85 MbSUCLG1: 84,423,526–84,460,045, reverse strandSUCLG1DNAH6: 84,516,498–84,819,589, forward strandDNAH6TRABD2A: 84,821,647–84,907,008, reverse strandTRABD2ATMSB10: 84,904,923–84,906,680, forward strandTMSB10KCMF1: 84,971,093–85,059,472, forward strandKCMF1TCF7L1: 85,133,348–85,310,388, forward strandTCF7L1Diagram of DNAH6: 77 exons on the forward strand of chromosome 2Exon 1: 84,516,498–84,516,583, 86 basesExon 2: 84,517,819–84,518,051, 233 basesExon 3: 84,525,565–84,525,738, 174 basesExon 4: 84,528,904–84,529,166, 263 basesExon 5: 84,544,233–84,544,500, 268 basesExon 6: 84,547,268–84,547,402, 135 basesExon 7: 84,547,492–84,547,612, 121 basesExon 8: 84,548,288–84,548,417, 130 basesExon 9: 84,549,889–84,550,057, 169 basesExon 10: 84,552,918–84,553,034, 117 basesExon 11: 84,557,735–84,557,935, 201 basesExon 12: 84,573,467–84,573,587, 121 basesExon 13: 84,577,257–84,577,408, 152 basesExon 14: 84,579,527–84,579,679, 153 basesExon 15: 84,583,999–84,584,250, 252 basesExon 16: 84,588,826–84,588,954, 129 basesExon 17: 84,593,972–84,594,085, 114 basesExon 18: 84,595,646–84,595,789, 144 basesExon 19: 84,604,339–84,604,551, 213 basesExon 20: 84,605,500–84,605,592, 93 basesExon 21: 84,606,976–84,607,095, 120 basesExon 22: 84,611,674–84,611,854, 181 basesExon 23: 84,616,886–84,616,982, 97 basesExon 24: 84,619,685–84,619,904, 220 basesExon 25: 84,621,191–84,621,355, 165 basesExon 26: 84,621,438–84,621,551, 114 basesExon 27: 84,624,265–84,624,390, 126 basesExon 28: 84,624,465–84,624,620, 156 basesExon 29: 84,624,902–84,625,063, 162 basesExon 30: 84,634,504–84,634,641, 138 basesExon 31: 84,637,210–84,637,377, 168 basesExon 32: 84,640,430–84,640,578, 149 basesExon 33: 84,641,947–84,642,054, 108 basesExon 34: 84,653,319–84,653,874, 556 basesExon 35: 84,654,660–84,654,782, 123 basesExon 36: 84,658,292–84,658,474, 183 basesExon 37: 84,659,026–84,659,169, 144 basesExon 38: 84,669,289–84,669,510, 222 basesExon 39: 84,670,328–84,670,475, 148 basesExon 40: 84,672,327–84,672,484, 158 basesExon 41: 84,677,005–84,677,136, 132 basesExon 42: 84,681,357–84,681,528, 172 basesExon 43: 84,685,326–84,685,472, 147 basesExon 44: 84,686,484–84,686,557, 74 basesExon 45: 84,688,439–84,688,593, 155 basesExon 46: 84,694,249–84,694,480, 232 basesExon 47: 84,697,575–84,697,727, 153 basesExon 48: 84,699,594–84,699,734, 141 basesExon 49: 84,701,097–84,701,339, 243 basesExon 50: 84,703,395–84,703,562, 168 basesExon 51: 84,704,067–84,704,302, 236 basesExon 52: 84,705,486–84,705,747, 262 basesExon 53: 84,706,896–84,707,019, 124 basesExon 54: 84,707,520–84,707,716, 197 basesExon 55: 84,709,343–84,709,546, 204 basesExon 56: 84,710,287–84,710,412, 126 basesExon 57: 84,713,095–84,713,259, 165 basesExon 58: 84,715,560–84,715,627, 68 basesExon 59: 84,718,204–84,718,384, 181 basesExon 60: 84,722,625–84,722,804, 180 basesExon 61: 84,727,669–84,727,902, 234 basesExon 62: 84,733,444–84,733,579, 136 basesExon 63: 84,745,080–84,745,249, 170 basesExon 64: 84,762,755–84,762,945, 191 basesExon 65: 84,781,493–84,781,653, 161 basesExon 66: 84,784,722–84,784,810, 89 basesExon 67: 84,785,610–84,785,756, 147 basesExon 68: 84,787,164–84,787,302, 139 basesExon 69: 84,796,306–84,796,425, 120 basesExon 70: 84,797,537–84,797,658, 122 basesExon 71: 84,805,665–84,805,794, 130 basesExon 72: 84,808,415–84,808,542, 128 basesExon 73: 84,812,341–84,812,526, 186 basesExon 74: 84,813,058–84,813,130, 73 basesExon 75: 84,813,971–84,814,122, 152 basesExon 76: 84,815,861–84,816,083, 223 basesExon 77: 84,819,305–84,819,589, 285 bases110203040506070775′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 12.8 kb of the gene's 303.1 kb; 12,477 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DNAH6 gene: dynein axonemal heavy chain 6. Retrieved 17 October 2026, from https://dantelabs.com/genes/dnah6

Vancouver

Dante Labs. DNAH6 gene: dynein axonemal heavy chain 6 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dnah6

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