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Gene

CIROZ

ciliated left-right organizer protein containing ZP-N domains

Summary

Cytogenetic location
1p36.22
Coordinates
Chromosome 1: 10,946,475–10,982,076 (GRCh38)
Exons
13 exons across 35.6 kb
Protein
823 amino acids
Also known as
FLJ37118
Previous symbols
C1orf127
MANE Select transcript
ENST00000377004.9NM_001170754.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CIROZ yet. The test sequences your whole genome, so your data includes it all the same.

How CIROZ is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where CIROZ sits. CIROZ and 10 genes near it on chromosome 1, from 10,464,276 to 11,464,275.Chromosome 11p36.22p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4410.6 Mb10.8 Mb11 Mb11.2 Mb11.4 MbDFFA: 10,456,522–10,472,582, reverse strandDFFAPEX14: 10,472,288–10,630,758, forward strandPEX14CASZ1: 10,636,601–10,796,658, reverse strandCASZ1CIROZ: 10,946,475–10,982,076, reverse strandCIROZTARDBP: 11,012,344–11,037,991, forward strandTARDBPMASP2: 11,022,009–11,047,273, reverse strandMASP2SRM: 11,054,584–11,060,078, reverse strandSRMEXOSC10: 11,066,613–11,099,907, reverse strandEXOSC10MTOR: 11,106,531–11,262,556, reverse strandMTORANGPTL7: 11,189,348–11,195,981, forward strandANGPTL7UBIAD1: 11,273,189–11,297,104, forward strandUBIAD1Diagram of CIROZ: 13 exons on the reverse strand of chromosome 1Exon 12: 1 known disease-causing siteExon 11: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 13: 10,946,475–10,946,741, 267 basesExon 12: 10,947,643–10,948,844, 1,202 basesExon 11: 10,949,624–10,949,814, 191 basesExon 10: 10,954,019–10,954,142, 124 basesExon 9: 10,954,990–10,955,186, 197 basesExon 8: 10,957,023–10,957,107, 85 basesExon 7: 10,957,616–10,957,753, 138 basesExon 6: 10,958,714–10,958,752, 39 basesExon 5: 10,964,128–10,964,271, 144 basesExon 4: 10,966,358–10,966,482, 125 basesExon 3: 10,969,970–10,970,089, 120 basesExon 2: 10,976,156–10,976,256, 101 basesExon 1: 10,982,012–10,982,076, 65 bases131211109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.8 kb of the gene's 35.6 kb; 2,472 of those bases code for the protein.

How a genome test reads CIROZ

3

positions in CIROZ where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 35.6 kb of CIROZ, introns included, not only the 2.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CIROZ gene: ciliated left-right organizer protein containing ZP-N domains. Retrieved 17 October 2026, from https://dantelabs.com/genes/ciroz

Vancouver

Dante Labs. CIROZ gene: ciliated left-right organizer protein containing ZP-N domains [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ciroz

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