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Trait

Left Isomerism

A type of heterotaxy where some paired structures on opposite sides of the left-right axis of the body are symmetrical mirror images of each other, and have the morphology of the normal left-sided structures.

HPO HP:0031854

Summary

Also called
Left-sided isomerism
Body system
Growth abnormality

4 genes linked to Left Isomerism

Changes in these genes cause rare conditions in which Left Isomerism is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
CIROZciliated left-right organizer protein containing ZP-N domainsAlwaysIn 1 condition
DNAH9dynein axonemal heavy chain 9Sometimes (5–29%)In 1 condition
SOX17SRY-box transcription factor 17Sometimes (5–29%)In 1 condition
CIROPciliated left-right organizer metallopeptidaseRarely (1–4%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Broader traits

Isomerism

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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