Traits

Traits linked to CD55

CD55 molecule (Cromer blood group)

The Human Phenotype Ontology links 28 traits to CD55, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the digestive system

Trait	How often it is seen
Malabsorption	Always
Abdominal pain	Often (30–79%)
Diarrhea	Often (30–79%)
Vomiting	Often (30–79%)
Protein-losing enteropathy	Rarely (1–4%)
Abnormality of the intestine	Not recorded
Accumulation of fluid in the abdomen	Not recorded
Enlarged liver	Not recorded
Intestinal obstruction	Not recorded

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
Low number of red blood cells or hemoglobin	Very often (80–99%)
Blood clot in liver vein	Sometimes (5–29%)
Increased number of platelets in blood	Sometimes (5–29%)
Iron deficiency anemia	Not recorded

Laboratory abnormality

Trait	How often it is seen
Fluid retention	Very often (80–99%)
Low albumin	Very often (80–99%)
Decreased protein levels in blood	Not recorded
Generalized edema	Not recorded

Abnormality of the cardiovascular system

Trait	How often it is seen
Intestinal lymphangiectasia	Often (30–79%)
Budd-Chiari syndrome	Sometimes (5–29%)
Blood clot in artery of lung	Not recorded

Abnormality of limbs

Trait	How often it is seen
Clubbing of fingers	Often (30–79%)
Clubbing of fingers and toes	Not recorded

Abnormality of the immune system

Trait	How often it is seen
Recurrent chest infections	Often (30–79%)
Recurrent infections	Not recorded

Abnormal cellular phenotype

Trait	How often it is seen
Decreased circulating antibody level	Always

Abnormality of the endocrine system

Trait	How often it is seen
Underactive thyroid	Sometimes (5–29%)

Constitutional symptom

Trait	How often it is seen
Joint pain	Sometimes (5–29%)

Growth abnormality

Trait	How often it is seen
Growth delay	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to CD55 and how often each is seen. Find out more at hpo.jax.org.

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