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Gene

RPL18

ribosomal protein L18

Summary

Cytogenetic location
19q13.33
Coordinates
Chromosome 19: 48,615,331–48,619,178 (GRCh38)
Exons
7 exons across 3.8 kb
Protein
188 amino acids
Also known as
L18, eL18
MANE Select transcript
ENST00000549920.6NM_000979.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RPL18 yet. The test sequences your whole genome, so your data includes it all the same.

How RPL18 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 19, with a bracket where RPL18 sits. RPL18 and 53 genes near it on chromosome 19, from 48,117,255 to 49,117,254.Chromosome 1919q13.33p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4348.2 Mb48.4 Mb48.6 Mb48.8 Mb49 MbLIG1: 48,115,444–48,170,654, reverse strandLIG1ZSWIM9: 48,170,645–48,197,624, forward strandZSWIM9CARD8: 48,180,770–48,255,976, reverse strandCARD8ZNF114: 48,270,041–48,289,292, forward strandZNF114ODAD1: 48,296,355–48,321,971, reverse strandODAD1EMP3: 48,321,310–48,330,560, forward strandEMP3TMEM143: 48,329,918–48,364,245, reverse strandTMEM143SYNGR4: 48,364,260–48,376,377, forward strandSYNGR4KDELR1: 48,382,558–48,393,837, reverse strandKDELR1GRIN2D: 48,393,668–48,444,931, forward strandGRIN2DGRWD1: 48,445,512–48,458,382, forward strandKCNJ14: 48,454,464–48,466,980, forward strandKCNJ14: 48,465,837–48,472,431, forward strandCYTH2: 48,469,203–48,482,314, forward strandCYTH2LMTK3: 48,485,271–48,513,935, reverse strandLMTK3SULT2B1: 48,552,140–48,599,425, forward strandSACK1E: 48,599,961–48,615,093, reverse strandSACK1ESPACA4: 48,606,742–48,607,962, forward strandSPACA4RPL18: 48,615,331–48,619,178, reverse strandRPL18SPHK2: 48,619,291–48,630,717, forward strandSPHK2DBP: 48,630,030–48,637,695, reverse strandCA11: 48,637,946–48,646,386, reverse strandNTN5: 48,661,407–48,673,081, reverse strandNTN5FUT2: 48,695,953–48,705,951, forward strandFUT2MAMSTR: 48,711,737–48,719,966, reverse strandMAMSTRRASIP1: 48,720,571–48,740,616, reverse strandRASIP1IZUMO1: 48,740,852–48,746,909, reverse strandIZUMO1FUT1: 48,748,011–48,755,390, reverse strandFUT1FGF21: 48,755,524–48,758,333, forward strandBCAT2: 48,795,061–48,811,066, reverse strandBCAT2HSD17B14: 48,813,014–48,837,064, reverse strandHSD17B14PLEKHA4: 48,837,091–48,868,855, reverse strandPLEKHA4PPP1R15A: 48,872,212–48,879,061, forward strandPPP1R15ATULP2: 48,880,965–48,898,744, reverse strandTULP2NUCB1: 48,900,050–48,923,958, forward strandNUCB1DHDH: 48,933,517–48,944,969, forward strandDHDHBAX: 48,954,815–48,961,806, forward strandBAXFTL: 48,965,275–48,967,896, forward strandFTLGYS1: 48,968,125–48,993,349, reverse strandGYS1RUVBL2: 48,993,476–49,017,868, forward strandRUVBL2LHB: 49,015,980–49,017,091, reverse strandLHBSAXO3: 49,017,968–49,020,549, reverse strandSAXO3CGB3: 49,022,869–49,024,360, reverse strand: 49,022,953–49,036,895, reverse strandCGB2: 49,031,890–49,033,238, forward strandCGB1: 49,035,569–49,036,895, reverse strandCGB5: 49,043,595–49,045,312, forward strandCGB8: 49,047,638–49,049,125, reverse strandCGB7: 49,054,274–49,058,860, reverse strandCGB7: 49,055,793–49,065,076, reverse strandNTF4: 49,061,066–49,065,076, reverse strandKCNA7: 49,067,397–49,072,702, reverse strandKCNA7SNRNP70: 49,085,164–49,108,618, forward strandLIN7B: 49,114,324–49,118,463, forward strandLIN7BDiagram of RPL18: 7 exons on the reverse strand of chromosome 19Exon 5: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 7: 48,615,331–48,615,447, 117 basesExon 6: 48,615,877–48,615,946, 70 basesExon 5: 48,616,079–48,616,202, 124 basesExon 4: 48,616,726–48,616,824, 99 basesExon 3: 48,617,316–48,617,423, 108 basesExon 2: 48,617,791–48,617,877, 87 basesExon 1: 48,619,141–48,619,178, 38 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.6 kb of the gene's 3.8 kb; 567 of those bases code for the protein.

How a genome test reads RPL18

2

positions in RPL18 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 3.8 kb of RPL18, introns included, not only the 0.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RPL18 gene: ribosomal protein L18. Retrieved 16 October 2026, from https://dantelabs.com/genes/rpl18

Vancouver

Dante Labs. RPL18 gene: ribosomal protein L18 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/rpl18

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