Trait
Abnormal circulating insulin concentration
An abnormal concentration of insulin in the body.
Summary
- Also called
- Abnormal insulin level
- Body system
- Abnormality of the endocrine system
Reference genomeGRCh38hg38
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Get my Genome Test16 genes linked to Abnormal circulating insulin concentration
Changes in these genes cause rare conditions in which Abnormal circulating insulin concentration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AKT2AKT serine/threonine kinase 2 | Very often (80–99%) | In 1 condition |
| ABCC8ATP binding cassette subfamily C member 8 | Often (30–79%) | In 1 condition |
| APPL1adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 | Often (30–79%) | In 1 condition |
| BLKBLK proto-oncogene, Src family tyrosine kinase | Often (30–79%) | In 1 condition |
| CELcarboxyl ester lipase | Often (30–79%) | In 1 condition |
| GCKglucokinase | Often (30–79%) | In 1 condition |
| HNF1AHNF1 homeobox A | Often (30–79%) | In 1 condition |
| HNF4Ahepatocyte nuclear factor 4 alpha | Often (30–79%) | In 1 condition |
| INSinsulin | Often (30–79%) | In 1 condition |
| KCNJ11potassium inwardly rectifying channel subfamily J member 11 | Often (30–79%) | In 1 condition |
| KLF11KLF transcription factor 11 | Often (30–79%) | In 1 condition |
| NEUROD1neuronal differentiation 1 | Often (30–79%) | In 1 condition |
| PAX4paired box 4 | Often (30–79%) | In 1 condition |
| PDX1pancreatic and duodenal homeobox 1 | Often (30–79%) | In 1 condition |
| SECISBP2SECIS binding protein 2 | Sometimes (5–29%) | In 1 condition |
| SLC5A2solute carrier family 5 member 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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