Trait

Abnormal cerebral cortex morphology

Any structural abnormality of the cerebral cortex.

Also called: Abnormality of the cerebral cortex
Body system: Abnormality of the nervous system

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5 genes linked to Abnormal cerebral cortex morphology

Changes in these genes cause rare conditions in which Abnormal cerebral cortex morphology is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
ERMARDER membrane associated RNA degradation	Very often (80–99%)	In 1 condition
NSDHLNAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL	Very often (80–99%)	In 1 condition
ZNF335zinc finger protein 335	Very often (80–99%)	In 1 condition
CLP1cleavage factor polyribonucleotide kinase subunit 1	Often (30–79%)	In 1 condition
SONSON DNA and RNA binding protein	Often (30–79%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

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Broader traits

Abnormal cerebral morphology

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

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