Variants
WT1 variants
The 19 WT1 variants with a page here, most review stars first. Each page describes ClinVar's public record of the variant, never a result.
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
| Variant | HGVS c. | Exon or intron | Position (GRCh38) | ClinVar classification | Review status |
|---|---|---|---|---|---|
| c.965+1G>A | Intron 4 | 32,417,576 | Likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts | |
| c.1447+4C>T1432+4C>T | Intron 9 | 32,391,968 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts | |
| c.1447+5G>A1432+5G>A | Intron 9 | 32,391,967 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts | |
| c.1448-1G>A | Intron 9 | 32,389,180 | Likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts | |
| G152Afs*11 | c.455del | Exon 1 | 32,434,905 | Pathogenic/likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| H446Q | c.1338C>A | Exon 8 | 32,392,682 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| H450Y | c.1348C>T | Exon 8 | 32,392,672 | Pathogenic/likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| P137Rfs*26 | c.410del | Exon 1 | 32,434,950 | Pathogenic/likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| Q462X | c.1384C>T | Exon 9 | 32,392,035 | Likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R374X | c.1120C>T | Exon 7 | 32,396,401 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R385Gfs*5 | c.1153delinsGG | Exon 7 | 32,396,368 | Pathogenic/likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R435X | c.1303C>T | Exon 8 | 32,392,717 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R439H | c.1316G>A | Exon 8 | 32,392,704 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R463Q | c.1388G>A | Exon 9 | 32,392,031 | Pathogenic/likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R463X | c.1387C>T | Exon 9 | 32,392,032 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R467Q | c.1400G>A | Exon 9 | 32,392,019 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R467W | c.1399C>T | Exon 9 | 32,392,020 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| R500W | c.1498C>T | Exon 10 | 32,389,129 | Likely pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |
| T279Hfs*19 | c.834dup | Exon 3 | 32,428,008 | Pathogenic | 2 stars out of 4 criteria provided, multiple submitters, no conflicts |