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Gene

QARS1

glutaminyl-tRNA synthetase 1

Summary

Cytogenetic location
3p21.31
Coordinates
Chromosome 3: 49,095,932–49,104,757 (GRCh38)
Exons
24 exons across 8.8 kb
Protein
775 amino acids
Previous symbols
QARS
MANE Select transcript
ENST00000306125.12NM_005051.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads QARS1 yet. The test sequences your whole genome, so your data includes it all the same.

How QARS1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 3, with a bracket where QARS1 sits. QARS1 and 33 genes near it on chromosome 3, from 48,600,345 to 49,600,344.Chromosome 33p21.31p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2948.8 Mb49 Mb49.2 Mb49.4 Mb49.6 MbUQCRC1: 48,598,990–48,610,976, reverse strandUQCRC1TMEM89: 48,620,759–48,621,769, reverse strandTMEM89SLC26A6: 48,625,718–48,635,510, reverse strandSLC26A6CELSR3: 48,636,463–48,662,886, reverse strandCELSR3NCKIPSD: 48,662,986–48,686,364, reverse strandNCKIPSDIP6K2: 48,688,003–48,740,353, reverse strandIP6K2PRKAR2A: 48,744,591–48,847,894, reverse strandPRKAR2ASLC25A20: 48,856,926–48,898,993, reverse strandSLC25A20ARIH2: 48,918,217–48,986,382, forward strandARIH2P4HTM: 48,989,858–49,007,153, forward strandWDR6: 49,007,062–49,015,953, forward strandDALRD3: 49,015,474–49,022,293, reverse strandNDUFAF3: 49,020,459–49,027,593, forward strandNDUFAF3IMPDH2: 49,024,315–49,029,452, reverse strandIMPDH2: 49,024,345–49,094,071, reverse strandQRICH1: 49,029,700–49,094,545, reverse strandQRICH1QARS1: 49,095,932–49,104,757, reverse strandQARS1USP19: 49,105,758–49,120,940, reverse strandUSP19LAMB2: 49,121,113–49,133,118, reverse strandLAMB2CCDC71: 49,161,063–49,166,357, reverse strandCCDC71KLHDC8B: 49,171,239–49,176,487, forward strandKLHDC8BCIMIP7: 49,177,634–49,191,858, reverse strandCIMIP7IHO1: 49,198,428–49,277,629, forward strandIHO1C3orf62: 49,268,596–49,277,236, reverse strandC3orf62USP4: 49,277,144–49,340,712, reverse strandUSP4GPX1: 49,357,174–49,358,605, reverse strandGPX1: 49,357,176–49,412,051, reverse strandRHOA: 49,359,136–49,412,998, reverse strandRHOATCTA: 49,412,212–49,455,826, forward strandAMT: 49,416,771–49,422,685, reverse strandAMT: 49,416,777–49,429,314, reverse strandNICN1: 49,422,333–49,429,331, reverse strandDAG1: 49,468,649–49,535,624, forward strandDAG1BSN: 49,554,477–49,671,549, forward strandBSNDiagram of QARS1: 24 exons on the reverse strand of chromosome 3Exon 22: 2 known disease-causing sitesExon 21: 2 known disease-causing sitesExon 20: 2 known disease-causing sitesExon 18: 5 known disease-causing sitesExon 17: 5 known disease-causing sitesExon 16: 4 known disease-causing sitesExon 15: 4 known disease-causing sitesExon 14: 4 known disease-causing sitesExon 13: 2 known disease-causing sitesExon 12: 2 known disease-causing sitesExon 11: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 5: 2 known disease-causing sitesExon 4: 3 known disease-causing sitesExon 3: 1 known disease-causing siteExon 2: 3 known disease-causing sitesExon 1: 5 known disease-causing sitesExon 24: 49,095,932–49,096,079, 148 basesExon 23: 49,097,992–49,098,117, 126 basesExon 22: 49,098,192–49,098,258, 67 basesExon 21: 49,098,353–49,098,480, 128 basesExon 20: 49,098,600–49,098,692, 93 basesExon 19: 49,098,885–49,098,989, 105 basesExon 18: 49,099,110–49,099,253, 144 basesExon 17: 49,099,344–49,099,431, 88 basesExon 16: 49,099,510–49,099,647, 138 basesExon 15: 49,099,761–49,099,853, 93 basesExon 14: 49,099,961–49,100,091, 131 basesExon 13: 49,100,190–49,100,298, 109 basesExon 12: 49,100,380–49,100,458, 79 basesExon 11: 49,100,575–49,100,674, 100 basesExon 10: 49,101,355–49,101,441, 87 basesExon 9: 49,101,620–49,101,705, 86 basesExon 8: 49,101,828–49,101,899, 72 basesExon 7: 49,102,205–49,102,265, 61 basesExon 6: 49,102,419–49,102,472, 54 basesExon 5: 49,103,345–49,103,409, 65 basesExon 4: 49,103,631–49,103,706, 76 basesExon 3: 49,103,863–49,103,972, 110 basesExon 2: 49,104,324–49,104,471, 148 basesExon 1: 49,104,617–49,104,757, 141 bases2422201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 8.8 kb; 2,328 of those bases code for the protein.

How a genome test reads QARS1

67

positions in QARS1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 8.8 kb of QARS1, introns included, not only the 2.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). QARS1 gene: glutaminyl-tRNA synthetase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/qars1

Vancouver

Dante Labs. QARS1 gene: glutaminyl-tRNA synthetase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/qars1

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