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Gene

KLHDC8B

kelch domain containing 8B

Summary

Cytogenetic location
3p21.31
Coordinates
Chromosome 3: 49,171,598–49,176,486 (GRCh38)
Exons
6 exons across 4.9 kb
Protein
354 amino acids
Also known as
MGC35097
MANE Select transcript
ENST00000332780.4NM_173546.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KLHDC8B yet. The test sequences your whole genome, so your data includes it all the same.

How KLHDC8B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 3, with a bracket where KLHDC8B sits. KLHDC8B and 30 genes near it on chromosome 3, from 48,674,042 to 49,674,041.Chromosome 33p21.31p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2948.8 Mb49 Mb49.2 Mb49.4 Mb49.6 MbNCKIPSD: 48,662,986–48,686,364, reverse strandNCKIPSDIP6K2: 48,688,003–48,740,353, reverse strandIP6K2PRKAR2A: 48,744,591–48,847,894, reverse strandPRKAR2ASLC25A20: 48,856,926–48,898,993, reverse strandSLC25A20ARIH2: 48,918,217–48,986,382, forward strandARIH2P4HTM: 48,989,858–49,007,153, forward strandWDR6: 49,007,062–49,015,953, forward strandDALRD3: 49,015,474–49,022,293, reverse strandNDUFAF3: 49,020,459–49,027,593, forward strandNDUFAF3IMPDH2: 49,024,315–49,029,452, reverse strandIMPDH2: 49,024,345–49,094,071, reverse strandQRICH1: 49,029,700–49,094,545, reverse strandQRICH1QARS1: 49,095,932–49,105,130, reverse strandQARS1USP19: 49,105,758–49,120,940, reverse strandUSP19LAMB2: 49,121,113–49,133,118, reverse strandLAMB2CCDC71: 49,161,063–49,166,357, reverse strandCCDC71KLHDC8B: 49,171,598–49,176,486, forward strandKLHDC8BCIMIP7: 49,177,634–49,191,858, reverse strandCIMIP7IHO1: 49,198,428–49,277,629, forward strandIHO1C3orf62: 49,268,596–49,277,236, reverse strandC3orf62USP4: 49,277,144–49,340,712, reverse strandUSP4GPX1: 49,357,174–49,358,605, reverse strandGPX1: 49,357,176–49,412,051, reverse strandRHOA: 49,359,136–49,412,998, reverse strandRHOATCTA: 49,412,212–49,455,826, forward strandAMT: 49,416,771–49,422,685, reverse strandAMT: 49,416,777–49,429,314, reverse strandNICN1: 49,422,333–49,429,331, reverse strandDAG1: 49,468,649–49,535,624, forward strandDAG1BSN: 49,554,477–49,671,549, forward strandBSNAPEH: 49,673,818–49,683,973, forward strandAPEHDiagram of KLHDC8B: 6 exons on the forward strand of chromosome 3Exon 1: 49,171,598–49,171,685, 88 basesExon 2: 49,172,636–49,173,145, 510 basesExon 3: 49,174,239–49,174,403, 165 basesExon 4: 49,174,742–49,174,966, 225 basesExon 5: 49,175,062–49,175,163, 102 basesExon 6: 49,175,605–49,176,486, 882 bases1234565′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 4.9 kb; 1,065 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). KLHDC8B gene: kelch domain containing 8B. Retrieved 17 October 2026, from https://dantelabs.com/genes/klhdc8b

Vancouver

Dante Labs. KLHDC8B gene: kelch domain containing 8B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/klhdc8b

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