Traits

Traits linked to NR2F2

nuclear receptor subfamily 2 group F member 2

The Human Phenotype Ontology links 12 traits to NR2F2, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the cardiovascular system

Trait	How often it is seen
Hole in center of heart	Often (30–79%)
Hole in heart wall separating two lower heart chambers	Often (30–79%)
Secundum atrial septal defect	Often (30–79%)
Underdeveloped left heart	Often (30–79%)
Left ventricular outflow tract obstruction	Sometimes (5–29%)
Narrowing of aorta	Sometimes (5–29%)
Narrowing of aortic valve	Sometimes (5–29%)
Tetralogy of Fallot	Sometimes (5–29%)

Abnormality of the genitourinary system

Trait	How often it is seen
Ambiguous external genitalia	Always
Urogenital sinus anomaly	Often (30–79%)

Abnormality of the endocrine system

Trait	How often it is seen
Increased testosterone	Always

Abnormality of the musculoskeletal system

Trait	How often it is seen
Aplasia of the left hemidiaphragm	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to NR2F2 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test