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Gene

NFIB

nuclear factor I B

Summary

Cytogenetic location
9p23-p22.3
Coordinates
Chromosome 9: 14,081,848–14,314,141 (GRCh38)
Exons
11 exons across 232.3 kb
Protein
494 amino acids
Also known as
NFI-RED, NFIB2, NFIB3
MANE Select transcript
ENST00000380953.6NM_001190737.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NFIB yet. The test sequences your whole genome, so your data includes it all the same.

How NFIB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 9, with a bracket where NFIB sits. NFIB and 1 gene near it on chromosome 9, from 13,697,995 to 14,697,994.Chromosome 99p23-p22.3p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.313.8 Mb14 Mb14.2 Mb14.4 Mb14.6 MbNFIB: 14,081,848–14,314,141, reverse strandNFIBZDHHC21: 14,586,766–14,694,198, reverse strandZDHHC21Diagram of NFIB: 11 exons on the reverse strand of chromosome 9Exon 10: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 7: 1 known disease-causing siteExon 6: 3 known disease-causing sitesExon 2: 12 known disease-causing sitesExon 1: 1 known disease-causing siteExon 11: 14,081,848–14,088,326, 6,479 basesExon 10: 14,112,999–14,113,081, 83 basesExon 9: 14,116,208–14,116,346, 139 basesExon 8: 14,120,440–14,120,624, 185 basesExon 7: 14,125,632–14,125,766, 135 basesExon 6: 14,146,689–14,146,807, 119 basesExon 5: 14,150,145–14,150,265, 121 basesExon 4: 14,155,825–14,155,893, 69 basesExon 3: 14,179,727–14,179,780, 54 basesExon 2: 14,306,989–14,307,520, 532 basesExon 1: 14,313,482–14,314,141, 660 bases1110864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 8.6 kb of the gene's 232.3 kb; 1,485 of those bases code for the protein.

How a genome test reads NFIB

21

positions in NFIB where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 232.3 kb of NFIB, introns included, not only the 8.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NFIB gene: nuclear factor I B. Retrieved 16 October 2026, from https://dantelabs.com/genes/nfib

Vancouver

Dante Labs. NFIB gene: nuclear factor I B [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/nfib

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