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Gene

KAT8

lysine acetyltransferase 8

Summary

Cytogenetic location
16p11.2
Coordinates
Chromosome 16: 31,117,664–31,131,359 (GRCh38)
Exons
11 exons across 13.7 kb
Protein
458 amino acids
Also known as
MOF, FLJ14040, hMOF
Previous symbols
MYST1
MANE Select transcript
ENST00000219797.9NM_032188.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KAT8 yet. The test sequences your whole genome, so your data includes it all the same.

How KAT8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 16, with a bracket where KAT8 sits. KAT8 and 39 genes near it on chromosome 16, from 30,624,512 to 31,624,511.Chromosome 1616p11.2p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.330.8 Mb31 Mb31.2 Mb31.4 Mb31.6 MbPRR14: 30,650,696–30,656,427, forward strandPRR14FBRS: 30,658,431–30,670,810, forward strandFBRSSRCAP: 30,698,128–30,741,409, forward strand: 30,704,067–30,745,169, forward strandTMEM265: 30,737,880–30,745,196, forward strandPHKG2: 30,748,245–30,761,176, forward strandPHKG2CFAP119: 30,757,423–30,762,221, reverse strandCFAP119RNF40: 30,761,561–30,780,421, forward strandRNF40ZNF629: 30,778,456–30,787,214, reverse strandZNF629BCL7C: 30,818,695–30,894,302, reverse strandBCL7CCTF1: 30,896,607–30,903,547, forward strandCTF1FBXL19: 30,923,055–30,948,783, forward strandFBXL19ORAI3: 30,949,055–30,956,511, forward strandORAI3SETD1A: 30,957,294–30,984,664, forward strandSETD1AHSD3B7: 30,985,029–30,989,154, forward strandHSD3B7STX1B: 30,989,256–31,010,897, reverse strandSTX1BSTX4: 31,032,889–31,042,975, forward strandSTX4ZNF668: 31,059,772–31,074,240, reverse strandZNF646: 31,074,394–31,084,196, forward strandZNF646PRSS53: 31,083,437–31,089,628, reverse strand: 31,083,439–31,094,956, reverse strandVKORC1: 31,090,260–31,095,980, reverse strandBCKDK: 31,106,107–31,113,464, forward strandBCKDKKAT8: 31,117,664–31,131,359, forward strandKAT8PRSS8: 31,131,433–31,135,727, reverse strandPRSS8PRSS36: 31,138,926–31,150,213, reverse strandPRSS36FUS: 31,180,131–31,196,963, forward strandFUSPYCARD: 31,201,486–31,203,450, reverse strandPYCARDTRIM72: 31,214,017–31,231,537, forward strandTRIM72PYDC1: 31,215,962–31,217,162, reverse strandPYDC1ITGAM: 31,259,954–31,332,892, forward strandITGAMITGAX: 31,355,134–31,382,999, forward strandITGAXITGAD: 31,393,258–31,426,505, forward strandITGADCOX6A2: 31,427,731–31,428,433, reverse strandCOX6A2ZNF843: 31,432,593–31,444,323, reverse strandZNF843ARMC5: 31,458,080–31,467,172, forward strandARMC5TGFB1I1: 31,471,585–31,478,727, forward strandTGFB1I1SLC5A2: 31,483,002–31,490,860, forward strandRUSF1: 31,489,465–31,509,309, reverse strandRUSF1AHSP: 31,512,938–31,528,808, forward strandAHSPDiagram of KAT8: 11 exons on the forward strand of chromosome 16Exon 2: 2 known disease-causing sitesExon 5: 1 known disease-causing siteExon 1: 31,117,664–31,117,892, 229 basesExon 2: 31,120,186–31,120,260, 75 basesExon 3: 31,120,339–31,120,514, 176 basesExon 4: 31,127,035–31,127,088, 54 basesExon 5: 31,127,189–31,127,353, 165 basesExon 6: 31,128,050–31,128,139, 90 basesExon 7: 31,130,017–31,130,157, 141 basesExon 8: 31,130,267–31,130,360, 94 basesExon 9: 31,130,456–31,130,606, 151 basesExon 10: 31,130,746–31,130,900, 155 basesExon 11: 31,131,195–31,131,359, 165 bases1246810115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.5 kb of the gene's 13.7 kb; 1,377 of those bases code for the protein.

How a genome test reads KAT8

3

positions in KAT8 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 13.7 kb of KAT8, introns included, not only the 1.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). KAT8 gene: lysine acetyltransferase 8. Retrieved 16 October 2026, from https://dantelabs.com/genes/kat8

Vancouver

Dante Labs. KAT8 gene: lysine acetyltransferase 8 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/kat8

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