Gene
HID1
HID1 domain containing
- HGNC 15736(opens in a new tab)
- Ensembl gene ENSG00000167861(opens in a new tab)
- NCBI Gene 283987(opens in a new tab)
Summary
- Cytogenetic location
- 17q25.1
- Coordinates
- Chromosome 17: 74,950,742–74,972,759 (GRCh38)
- Exons
- 19 exons across 22 kb
- Protein
- 788 amino acids
- Also known as
- DMC1, HID-1
- Previous symbols
- C17orf28
- MANE Select transcript
- ENST00000425042.7NM_030630.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read HID1, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated report relevant to this gene
Epilepsy (Full Panel)
- Epilepsy
One of 171 genes linked to it
A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions.
- 2 GenCC submitters rate it definitive or strong
How HID1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.3 kb of the gene's 22 kb; 2,367 of those bases code for the protein.
How a genome test reads HID1
4
positions in HID1 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 22 kb of HID1, introns included, not only the 3.3 kb of exons.
Traits linked to HID1
The Human Phenotype Ontology lists these as features of the rare conditions HID1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Absent speech development
- Motor delay
- EEG with focal sharp slow waves
- EEG with generalized slow activity
- Grand mal seizures
- Thin corpus callosum
- Brain degeneration
- Focal impaired awareness seizure
Show 3 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
- The ACMG secondary findings list, SF v3.2.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). HID1 gene: HID1 domain containing. Retrieved 16 October 2026, from https://dantelabs.com/genes/hid1
Dante Labs. HID1 gene: HID1 domain containing [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/hid1
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks