Trait

Urethral valve

The presence of an abnormal membrane obstructing the urethra.

Body system: Abnormality of the genitourinary system

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/urethral-valve.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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4 genes linked to Urethral valve

Changes in these genes cause rare conditions in which Urethral valve is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
DACT1dishevelled binding antagonist of beta catenin 1	Sometimes (5–29%)	In 1 condition
SALL1spalt like transcription factor 1	Sometimes (5–29%)	In 2 conditions
HPSE2heparanase 2 (inactive)	Not recorded	In 1 condition
IGF2insulin like growth factor 2	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Congenital posterior urethral valve9 genes

Broader traits

Urethral obstruction

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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