Trait
Toe curvature
Clinical name: Toe clinodactyly
Bending or curvature of a toe in the tibial direction (i.e., towards the big toe).
Summary
- Also called
- Clinodactyly of feet
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test15 genes linked to Toe curvature
Changes in these genes cause rare conditions in which Toe curvature is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| DACT1dishevelled binding antagonist of beta catenin 1 | Often (30–79%) | In 1 condition |
| EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit | Often (30–79%) | In 1 condition |
| FLI1Fli-1 proto-oncogene, ETS transcription factor | Often (30–79%) | In 1 condition |
| SALL1spalt like transcription factor 1 | Often (30–79%) | In 1 condition |
| TSHZ3teashirt zinc finger homeobox 3 | Often (30–79%) | In 1 condition |
| ATP2B1ATPase plasma membrane Ca2+ transporting 1 | Sometimes (5–29%) | In 1 condition |
| BCL11ABCL11 transcription factor A | Sometimes (5–29%) | In 1 condition |
| RELREL proto-oncogene, NF-kB subunit | Sometimes (5–29%) | In 1 condition |
| RFX7regulatory factor X7 | Sometimes (5–29%) | In 1 condition |
| RSPRY1ring finger and SPRY domain containing 1 | Sometimes (5–29%) | In 1 condition |
| SATB2SATB homeobox 2 | Sometimes (5–29%) | In 1 condition |
| XPO1exportin 1 | Sometimes (5–29%) | In 1 condition |
| XYLT1xylosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| FLNAfilamin A | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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